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公开(公告)号：US20190054203A1
公开(公告)日：2019-02-21
申请号：US16169045
申请日：2018-10-24
发明人： Erez ILAN , Omri Faingold , Nataly Freizus , Ronen Eavri , Dwayne Looney , Sridevi Dhanaraj , James Galloway , Walter Danker
摘要： The invention relates to a hemostatic composition comprising a mixture of cellulose-based short and long fibers, preparation and use thereof.
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公开(公告)号：US20200171201A1
公开(公告)日：2020-06-04
申请号：US16783403
申请日：2020-02-06
发明人： Erez ILAN , Omri Faingold , Nataly Freizus , Ronen Eavri , Dwayne Looney , Sridevi Dhanaraj , James Galloway , Walter Danker
摘要： The present invention relates to improved hemostatic compositions comprising cellulose-based fibers supplemented with compounds, preparation and use thereof.
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公开(公告)号：US20170042523A1
公开(公告)日：2017-02-16
申请号：US15336997
申请日：2016-10-28
发明人： John Goodman , Jared Schneider , Kenneth M. Tamsula , Erez ILAN , Tamara Byk-Tennenbaum , John Anastasiadis
CPC分类号： A61B17/00491 , A61B50/30 , A61B2017/00495 , A61B2090/0808 , A61M5/19 , A61M5/31596
摘要： Apparatuses and methods for delivery of fluid materials, particularly multi-part fluid materials, including modular apparatuses in which various components are maintained separately until ready for use. Each fluid component is maintained in a separate housing until mixing of the fluid components is desired. Maintaining components separately until use allows for proper filling, sterilization, packaging and storing until use.
摘要翻译： 用于输送流体材料，特别是多部分流体材料的装置和方法，包括模块化装置，其中各种部件分开维持直到准备使用。 每个流体组分保持在单独的壳体中，直到需要混合流体组分。 单独维护组件直到使用才允许正确填充，灭菌，包装和储存，直到使用。
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公开(公告)号：US20160067406A1
公开(公告)日：2016-03-10
申请号：US14479435
申请日：2014-09-08
发明人： John Goodman , Jared Schneider , Kenneth M. Tamsula , Erez ILAN , Tamara Byk-Tennenbaum , John Anastasiadis
CPC分类号： A61B17/00491 , A61B50/30 , A61B2017/00495 , A61B2090/0808 , A61M5/19 , A61M5/31596
摘要： Apparatuses and methods for delivery of fluid materials, particularly multi-part fluid materials, including modular apparatuses in which various components are maintained separately until ready for use. Each fluid component is maintained in a separate housing until mixing of the fluid components is desired. Maintaining components separately until use allows for proper filling, sterilization, packaging and storing until use.
摘要翻译： 用于输送流体材料，特别是多部分流体材料的装置和方法，包括模块化装置，其中各种部件分开维持直到准备使用。 每个流体组分保持在单独的壳体中，直到需要混合流体组分。 单独维护组件直到使用才允许正确填充，灭菌，包装和储存，直到使用。
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公开(公告)号：US20210154224A1
公开(公告)日：2021-05-27
申请号：US17167428
申请日：2021-02-04
发明人： James Galloway , Tamara BYK-TENNENBAUM , Erez ILAN , Lior WEISSMAN , Sivan DORON , Eve MONTIA
IPC分类号： A61K31/717 , A61K31/704 , A61L24/00 , A61L15/28 , A61L24/08 , A61L15/44
摘要： Provided is a method of enhancing toxicity of a glycolytic dependent compound towards a cell, tissue and/or organ e.g. a diseased cell, tissue and/or organ, the method comprises contacting Oxidized Regenerated Cellulose (ORC) and/or Oxidized Cellulose (OC); and a glycolytic dependent compound with the cell, tissue and/or organ. The ORC and/or OC; and the glycolytic dependent compound are contacted with the cell, tissue and/or organ in a non-blended form.
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公开(公告)号：US20220054527A1
公开(公告)日：2022-02-24
申请号：US17518415
申请日：2021-11-03
发明人： James Galloway , Tamara BYK-TENNENBAUM , Erez ILAN , Lior WEISSMAN , Sivan DORON , Eve MONTIA , Niels-Derrek Schmitz
IPC分类号： A61K31/717 , A61K31/704 , A61L24/00 , A61L15/28 , A61L24/08 , A61L15/44
摘要： Provided are implants and a glycolytic dependent compound for use in enhancing toxicity of the glycolytic dependent compound towards a cell, tissue and/or organ e.g., a diseased cell, tissue and/or organ, wherein the implant and the glycolytic dependent compound are contacted with the cell, tissue and/or organ in a non-blended form.
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公开(公告)号：US20210154358A1
公开(公告)日：2021-05-27
申请号：US17167492
申请日：2021-02-04
发明人： Erez ILAN , Omri Faingold , Nataly Freizus , Ronen Eavri , Dwayne Looney , Sridevi Dhanaraj , James Galloway , Walter Danker
摘要： The invention relates to a hemostatic composition comprising a mixture of cellulose-based short and long fibers, preparation and use thereof.
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公开(公告)号：US20190060514A1
公开(公告)日：2019-02-28
申请号：US16167924
申请日：2018-10-23
发明人： Erez ILAN , Omri Faingold , Nataly Freizus , Ronen Eavri , Dwayne Looney , Sridevi Dhanaraj , James Galloway , Walter Danker
摘要： The present invention relates to improved hemostatic compositions comprising cellulose-based fibers supplemented with compounds, preparation and use thereof.
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9.发明申请公开(公告)号：US20210052263A1
公开(公告)日：2021-02-25
申请号：US17082671
申请日：2020-10-28
发明人： Erez ILAN , Yotam GURMAN , Moti MERON
摘要： Disclosed are devices and methods suitable for application of a curable fluid composition to a bodily organ, such as to a lower portion of a bodily organ. The device comprises a monolithic piece of material having a lower surface, two spaced-apart sides, and two spaced-apart walls connecting the two spaced-apart sides. A receptacle for containing the curable fluid composition is defined by the lower surface, the two sides, and the two walls. At least a portion of the height of the two walls is less than the height of at least a portion of the two sides. The device is deployable underneath the bodily organ such that a lower portion of the bodily organ is supported by at least a portion of each of the two walls.
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公开(公告)号：US20240173388A1
公开(公告)日：2024-05-30
申请号：US18418690
申请日：2024-01-22
发明人： Erez ILAN , Omri FAINGOLD , Sivan DORON
CPC分类号： A61K38/4833 , A61K47/02 , A61K47/10 , A61K47/42 , A61P7/04 , C12Y304/21005
摘要： The present invention provides methods for large scale preparation of sterile stable liquid thrombin composition comprised of glycerol; stable liquid thrombin compositions; and hemostatic composition and kits. The present invention further provides hemostatic compositions comprised of liquid thrombin, glycerol and gelatin. Further provided herein is a method for the large-scale production of a sterile liquid thrombin composition comprised of glycerol.
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