公开(公告)号：US20120029328A1

公开(公告)日：2012-02-02

申请号：US13271732

申请日：2011-10-12

申请人： Etsuro SHIMIZU ,  Kazuya MATSUMOTO ,  Ryo OTA ,  Atsushi MATSUMOTO

发明人： Etsuro SHIMIZU ,  Kazuya MATSUMOTO ,  Ryo OTA ,  Atsushi MATSUMOTO

IPC分类号： A61B5/1455

CPC分类号： G01N21/77 ,  A61B5/14532 ,  A61B5/1459 ,  G01N2021/7753 ,  G01N2021/7786

摘要： A needle-type fluorescence sensor that measures glucose based on fluorescence produced by excitation light is provided. The needle-type fluorescence sensor includes a needle body section including a sensor portion disposed in a needle distal end portion and metal lines disposed from the sensor portion to a needle proximal end portion, and a connector which is integrated with the needle body section and in which the metal lines extend. The sensor portion includes a silicon substrate having first and second principal surfaces, a PD device that converts fluorescence into an electric signal, an LED device that transmits fluorescence and emits excitation light, and an indicator layer that interacts with an analyte under the excitation light to produce fluorescence. The PD device, the LED device, and the indicator layer overlap with each other above the first principal surface of the silicon substrate.

摘要翻译： 提供了一种根据由激发光产生的荧光测量葡萄糖的针型荧光传感器。 针型荧光传感器包括：针体部，其包括设置在针前端部的传感器部和从传感器部到针基端部的金属线;以及连接器，其与针体部一体化， 金属线延伸。 传感器部分包括具有第一和第二主表面的硅衬底，将荧光转换为电信号的PD器件，透射荧光并发射激发光的LED器件，以及在激发光下与分析物相互作用的指示器层 产生荧光。 PD器件，LED器件和指示层在硅衬底的第一主表面之上彼此重叠。