专利检索 ap:("Eun Sook KIM" OR "Hee Cheol KIM" OR "Bo Sung KWON" OR "Sangmin YUN" OR "Mi Young KO" OR "Cheol Kyung KIM" OR "Kwee Hyun SUH") AND inv:"Cheol Kyung KIM" 第 1 页

1.

发明申请
METHOD PREPARATION CLOPIDOGREL AND INTERMEDIATES USED THEREIN 失效
标题翻译：方法制备石蜡和其使用的中间体

公开(公告)号：US20090318701A1

公开(公告)日：2009-12-24

申请号：US12549850

申请日：2009-08-28

申请人： Eun Sook KIM , Hee Cheol KIM , Bo Sung KWON , Sangmin YUN , Mi Young KO , Cheol Kyung KIM , Kwee Hyun SUH

发明人： Eun Sook KIM , Hee Cheol KIM , Bo Sung KWON , Sangmin YUN , Mi Young KO , Cheol Kyung KIM , Kwee Hyun SUH

IPC分类号： C07D495/04

CPC分类号： C07D495/04

摘要： Optically pure clopidogrel can be prepared in a high yield by optically resolving a racemic form of the compound of formula (II) using an optically active amine to form the optically active form of the compound of formula (III) or its acid-addition salt; and methylating the compound of formula (III) or its acid-addition salt.

摘要翻译： 光学纯氯吡格雷可以通过光学拆分式（II）化合物的外消旋形式，使用光学活性胺形成式（III）化合物或其酸加成盐的光学活性形式，以高产率制备; 并使式（III）化合物或其酸加成盐进行甲基化。