专利检索 ap:("FEED RESEARCH INSTITUTE, CHINESE ACADEMY OF AGRICULTURAL SCIENCES") AND inv:"Yangyang Li" 第 1 页

1.

发明授权
Phytase variants YkAPPA having improved pepsin resistance and increased catalytic efficiency 有权

公开(公告)号：US11028377B2

公开(公告)日：2021-06-08

申请号：US16477907

申请日：2018-01-15

申请人： FEED RESEARCH INSTITUTE, CHINESE ACADEMY OF AGRICULTURAL SCIENCES

发明人： Canfang Niu , Peilong Yang , Bin Yao , Yangyang Li , Dali Yu , Huiying Luo , Huoqing Huang , Yaru Wang

IPC分类号： C12N9/16 , C07K14/24

摘要： The present invention relates to the field of genetic engineering, particularly to phytase variants YkAPPA having amino acid sequence substituting Leucine at the 162th site of the sequence set forth in SEQ ID NO.1 with glycine or proline, or having amino acid sequence substituting glutamic acid at the 230th site of the sequence set forth in SEQ ID NO.1 with glycine, alanine, serine, threonine, aspartic acid, proline, or arginine, and having improved pepsin resistance and increased catalytic efficiency of 2.1 times of that of the wild phytase, in the benefit of the development of economical feed enzyme industry.