CENTRIFUGAL-DRIVEN MICROFLUIDIC PLATFORM AND METHOD OF USE THEREOF

    公开(公告)号:US20210387179A1

    公开(公告)日:2021-12-16

    申请号:US17342539

    申请日:2021-06-08

    Abstract: In this invention, chromatography is integrated on a centrifugal platform to enable low-cost automated purification. Differing from the traditional chromatography method, purification and separation of a centrifugal compound collecting platform disclosed in the present invention mainly uses a centrifugal force to drive the fluid to flow outward in the radial direction when the motor rotates. The compounds to be separated react with the column packing during the flow, and the compounds with different polarities in the sample are gradually separated. The flow of the fluid can be governed by the motor and the geometry of the fluidic design such that compounds with different characteristics can be separated and collected in different collecting chambers.

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