公开(公告)号：US20190169133A1

公开(公告)日：2019-06-06

申请号：US16272263

申请日：2019-02-11

Applicant: FUJIFILM Corporation

Inventor： Yusuke NAGATO ,  Shinsuke MIZUMOTO ,  Tatsuya MURAKAMI ,  Tomoyuki TANAKA

IPC: C07D239/48 ,  C07D403/06

Abstract: An object of the present invention is to provide a method for industrially manufacturing a nitrogen-containing heterocyclic compound which shows excellent FLT3 inhibitory activity and is useful as a pharmaceutical active ingredient of pharmaceutical products. The present invention provides a manufacturing method of a compound represented by General Formula [14] or a salt thereof (in the formula, R1 represents a C1-6 alkyl group which may be substituted; and R8 represents a leaving group or the like).

公开(公告)号：US20180127382A1

公开(公告)日：2018-05-10

申请号：US15867122

申请日：2018-01-10

Applicant: FUJIFILM Corporation

Inventor： Yusuke NAGATO ,  Shinsuke MIZUMOTO ,  Tatsuya MURAKAMI ,  Tomoyuki TANAKA

IPC: C07D239/48 ,  C07D403/06

Abstract: An object of the present invention is to provide a method for industrially manufacturing a nitrogen-containing heterocyclic compound which shows excellent FLT3 inhibitory activity and is useful as a pharmaceutical active ingredient of pharmaceutical products. The present invention provides a manufacturing method of a compound represented by General Formula [14] or a salt thereof (in the formula, R1 represents a C1-6 alkyl group which may be substituted; and R8 represents a leaving group or the like).