公开(公告)号：US20240094210A1

公开(公告)日：2024-03-21

申请号：US18261207

申请日：2022-01-17

申请人： FUJIREBIO INC.

发明人： Tomonori NISHII ,  Eriko SATO ,  Kumiko IIDA ,  Shintaro YAGI ,  Katsumi AOYAGI

IPC分类号： G01N33/574

CPC分类号： G01N33/57438 ,  G01N2333/4722 ,  G01N2470/04

摘要： A method for treating a specimen in soluble GPC3 immunoassay, the method including mixing a soluble GPC3-containing specimen with a reducing agent. A soluble GPC3 immunoassay method including the following (a) and (b): (a) mixing a soluble GPC3-containing specimen with a reducing agent; and (b) measuring the amount of soluble GPC3 in the mixture obtained in (a) using one or more kinds of antibodies against soluble GPC3. A soluble GPC3 immunoassay reagent including the following (a) and (b): (a) a reducing agent; and (b) one or more kinds of antibodies against soluble GPC3.

公开(公告)号：US20200371104A1

公开(公告)日：2020-11-26

申请号：US16768419

申请日：2018-11-22

申请人： FUJIREBIO INC.

发明人： Chiharu OHUE ,  Kumiko IIDA ,  Katsumi AOYAGI ,  Shintaro YAGI

IPC分类号： G01N33/576 ,  G01N33/563

摘要： Disclosed is a highly sensitive assay method and assay kit for HBsAg, which do not require treatment with a strong acid or alkali in the sample pretreatment, and which is less susceptible to influences by the autoantibodies. The assay method for hepatitis B virus s antigen in a sample separated from a living body includes: a pretreatment step of mixing a sample with a pretreatment reagent containing a reducing agent, to reduce hepatitis B virus s antigen; and an immunoassay step of subjecting the pretreated sample to an immunoassay of hepatitis B virus s antigen using at least one antibody or antigen-binding fragment thereof capable of antigen-antibody reaction with a reduced peptide composed of the amino acids at positions 98 to 179 of hepatitis B virus s antigen.

公开(公告)号：US20220326246A1

公开(公告)日：2022-10-13

申请号：US17639400

申请日：2020-09-01

申请人： FUJIREBIO INC.

发明人： Kazunori OKADA ,  Kumiko IIDA ,  Shintaro YAGI ,  Katsumi AOYAGI

IPC分类号： G01N33/574

摘要： A lectin-binding substance measurement method is a method for measuring a lectin-binding substance in a sample, and includes: a capturing step of bringing a capture carrier including a water-insoluble carrier and a molecule immobilized on the water-insoluble carrier, the molecule being a molecule capable of capturing a lectin-binding substance, into contact with the sample to cause the capture carrier to capture the lectin-binding substance; a washing step of removing contaminants unbound to the capture carrier; a releasing step of releasing the lectin-binding substance from the capture carrier to obtain a prepared sample; and a measuring step of measuring the lectin-binding substance in the prepared sample by using a lectin.

公开(公告)号：US20220326245A1

公开(公告)日：2022-10-13

申请号：US17639391

申请日：2020-09-01

申请人： FUJIREBIO INC.

发明人： Tomonori NISHII ,  Kazunori OKADA ,  Naoki ISHIKAWA ,  Kumiko IIDA ,  Shintaro YAGI ,  Katsumi AOYAGI

IPC分类号： G01N33/574

摘要： A lectin-binding substance measurement method is a method for measuring a lectin-binding substance in a sample, and includes a measuring step of bringing a blocked labeled lectin including a water-soluble carrier made of a first water-soluble polymer and a labeling substance and a lectin immobilized on the water-soluble carrier into contact with the sample.