公开(公告)号：US11911375B2

公开(公告)日：2024-02-27

申请号：US17098550

申请日：2020-11-16

Applicant: Fertin Pharma A/S

Inventor： Kent Albin Nielsen ,  Jessie Poulsen

IPC: A61K31/465 ,  A61K9/68 ,  A61K9/20 ,  A61K47/02 ,  A61K47/14 ,  A61K47/26 ,  A61K47/32 ,  A61K47/44

CPC classification number: A61K31/465 ,  A61K9/0058 ,  A61K9/2009 ,  A61K9/2018 ,  A61K9/2027 ,  A61K9/2054 ,  A61K9/2059 ,  A61K9/2068 ,  A61K47/02 ,  A61K47/14 ,  A61K47/26 ,  A61K47/32 ,  A61K47/44

Abstract: A solid oral nicotine formulation is disclosed, the formulation comprises a nicotine-ion exchange resin combination, and a salt comprising inorganic divalent cations, wherein the salt has a water-solubility of at least 5 grams per 100 mL of water measured at 25 degrees Celsius, atmospheric pressure and pH 7.0.

公开(公告)号：US20220152013A1

公开(公告)日：2022-05-19

申请号：US17098550

申请日：2020-11-16

Applicant: Fertin Pharma A/S

Inventor： Kent Albin Nielsen ,  Jessie Poulsen

IPC: A61K31/465 ,  A61K9/68 ,  A61K9/20 ,  A61K47/26 ,  A61K47/02 ,  A61K47/14 ,  A61K47/32 ,  A61K47/44

Abstract: A solid oral nicotine formulation is disclosed, the formulation comprises a nicotine-ion exchange resin combination, and a salt comprising inorganic divalent cations, wherein the salt has a water-solubility of at least 5 grams per 100 mL of water measured at 25 degrees Celsius, atmospheric pressure and pH 7.0.