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1.发明公开公开(公告)号：US20230192870A1
公开(公告)日：2023-06-22
申请号：US17812592
申请日：2022-07-14
发明人： Katherine E. Lewis , Serena Kimi Perna , Michael Carleton , Ke Xu , Penny Phillips , Dimple Pandya , Brian Wong , Julie Hambleton , Robert Sikorski , Emma Masteller , Kevin Hestir , David Bellovin , Janine Powers , Ernestine Lee
IPC分类号： C07K16/28 , A61K47/69 , A61K47/64 , A61P35/00 , A61K31/337 , A61K31/513 , A61K31/7068 , A61K39/395 , C12Q1/6886
CPC分类号： C07K16/2866 , A61K47/6929 , A61K47/643 , A61P35/00 , A61K31/337 , A61K31/513 , A61K31/7068 , A61K39/3955 , C07K16/2818 , C12Q1/6886 , A61K2039/507
摘要： The present invention relates to methods of treating pancreatic cancer with particular dosage regimes of antibodies that bind colony stimulating factor 1 receptor (CSF1R) (e.g. cabiralizumab) in combination with antibodies that bind programmed cell death 1 (PD-1) (e.g. nivolumab).
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公开(公告)号：US10975153B2
公开(公告)日：2021-04-13
申请号：US15319143
申请日：2015-06-18
发明人： Julie Hambleton , Emma Masteller , James Zanghi , Robert Sikorski , Hong Xiang
IPC分类号： C07K16/28 , A61K39/00 , A61K39/395
摘要： Methods of treating conditions with antibodies that bind colony stimulating factor 1 receptor (CSF1R) are provided. Such methods include, but are not limited to, methods of treating rheumatoid arthritis.
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3.发明申请公开(公告)号：US20160319028A1
公开(公告)日：2016-11-03
申请号：US15152161
申请日：2016-05-11
发明人： Brian Wong , Emma Masteller , Justin Wong , Haishan Lin
IPC分类号： C07K16/28
CPC分类号： C07K16/2866 , A61K39/3955 , A61K45/06 , A61K2039/505 , C07K16/2869 , C07K2317/24 , C07K2317/33 , C07K2317/51 , C07K2317/515 , C07K2317/54 , C07K2317/55 , C07K2317/565 , C07K2317/622 , C07K2317/73 , C07K2317/76 , C07K2317/92
摘要： Methods of treating conditions with antibodies that bind colony stimulating factor 1 receptor (CSF1R) are provided. Such methods include, but are not limited to, methods of treating rheumatoid arthritis and associated conditions, methods of treating systemic lupus erythematosus and associated conditions, and methods of treating multiple sclerosis.
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公开(公告)号：US20160152715A1
公开(公告)日：2016-06-02
申请号：US14925534
申请日：2015-10-28
发明人： Brian Wong , Julie Hambleton , Robert Sikorski , Emma Masteller , Kevin Hestir , David Bellovin , Katherine E. Lewis
CPC分类号： C07K16/2866 , A61K2039/505 , A61K2039/507 , A61K2039/54 , A61K2039/545 , C07K16/2803 , C07K16/2818 , C07K16/3046 , C07K16/3069 , C07K2317/24 , C07K2317/33 , C07K2317/565 , C07K2317/76 , C07K2317/90 , C07K2317/92
摘要： Methods of treating cancer with antibodies that bind colony stimulating factor 1 receptor (CSF1R) in combination with PD-1/PD-L1 inhibitors are provided.
摘要翻译： 提供了与PD-1 / PD-L1抑制剂结合使用结合集落刺激因子1受体（CSF1R）的抗体治疗癌症的方法。
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公开(公告)号：US11566076B2
公开(公告)日：2023-01-31
申请号：US16808910
申请日：2020-03-04
发明人： Brian Wong , Julie Hambleton , Robert Sikorski , Emma Masteller , Kevin Hestir , David Bellovin , Katherine E. Lewis
摘要： Methods of treating cancer with antibodies that bind colony stimulating factor 1 receptor (CSF1R) in combination with PD-1/PD-L1 inhibitors are provided.
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公开(公告)号：US11559583B2
公开(公告)日：2023-01-24
申请号：US16786158
申请日：2020-02-10
发明人： Emma Masteller , Thomas Brennan , David Bellovin , Kevin P. Baker , Brian Wong
摘要： Methods of treating cancer with antibodies that bind colony stimulating factor 1 receptor (CSF1R) in combination with one or more immune stimulating agents are provided.
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公开(公告)号：US11421034B2
公开(公告)日：2022-08-23
申请号：US16646690
申请日：2018-09-12
发明人： Katherine E. Lewis , Serena Kimi Perna , Michael Carleton , Ke Xu , Penny Phillips , Dimple Pandya , Brian Wong , Julie Hambleton , Robert Sikorski , Emma Masteller , Kevin Hestir , David Bellovin , Janine Powers , Ernestine Lee
IPC分类号： C07K16/28 , A61K47/69 , A61K47/64 , A61P35/00 , A61K31/337 , A61K31/513 , A61K31/7068 , A61K39/395 , C12Q1/6886 , A61K39/00
摘要： The present invention relates to methods of treating pancreatic cancer with particular dosage regimes of antibodies that bind colony stimulating factor 1 receptor (CSF1R) (e.g. cabiralizumab) in combination with antibodies that bind programmed cell death 1 (PD-1) (e.g. nivolumab).
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公开(公告)号：US20200299392A1
公开(公告)日：2020-09-24
申请号：US16808910
申请日：2020-03-04
发明人： Brian Wong , Julie Hambleton , Robert Sikorski , Emma Masteller , Kevin Hestir , David Bellovin , Katherine E. Lewis
摘要： Methods of treating cancer with antibodies that bind colony stimulating factor 1 receptor (CSF1R) in combination with PD-1/PD-L1 inhibitors are provided.
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9.发明申请METHODS OF TREATING CONDITIONS WITH ANTIBODIES THAT BIND COLONY STIMULATING FACTOR 1 RECEPTOR (CSF1R) 审中-公开用抗体结合刺激因子1受体（CSF1R）处理条件的方法公开(公告)号：US20160326254A1
公开(公告)日：2016-11-10
申请号：US15154822
申请日：2016-05-13
发明人： Brian Wong , Emma Masteller , Kris Reedquist
IPC分类号： C07K16/28 , A61K39/395
CPC分类号： C07K16/2866 , A61K39/3955 , A61K45/06 , A61K2039/505 , C07K2317/24 , C07K2317/92 , G01N2333/52 , G01N2333/96494 , G01N2800/52
摘要： Methods of reducing cytokine levels and methods of treating conditions with antibodies that bind colony stimulating factor 1 receptor (CSF1R) are provided. Such methods include, but are not limited to, methods of treating inflammatory conditions, such as rheumatoid arthritis.
摘要翻译： 提供了降低细胞因子水平的方法和用克隆集落刺激因子1受体（CSF1R）的抗体治疗病症的方法。 这些方法包括但不限于治疗炎症性疾病如风湿性关节炎的方法。
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公开(公告)号：US20230212299A1
公开(公告)日：2023-07-06
申请号：US18069511
申请日：2022-12-21
发明人： Brian Wong , Julie Hambleton , Robert Sikorski , Emma Masteller , Kevin Hestir , David Bellovin , Katherine E. Lewis
CPC分类号： C07K16/2863 , C07K16/2896 , A61P35/00 , C07K2317/565
摘要： Methods of treating cancer with antibodies that bind colony stimulating factor 1 receptor (CSF1R) in combination with PD-1/PD-L1 inhibitors are provided.
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