公开(公告)号：US20140349275A1

公开(公告)日：2014-11-27

申请号：US14264462

申请日：2014-04-29

Applicant: Focus Diagnostics, Inc.

Inventor： Fan Chen ,  Lilly I. Kong ,  Jules Chen ,  Mehrdad Jannatipour

IPC: C12Q1/70

CPC classification number: C12Q1/701 ,  C12N2710/22011 ,  C12Q2600/158

Abstract: The invention provides methods and compositions for rapid, sensitive, and highly specific nucleic acid-based (e.g., DNA based) detection of a BK virus in a sample. In general, the methods involve detecting a target nucleic acid having a target sequence of a conserved region of BK viral genomes. The invention also features compositions, including primers, probes, and kits, for use in the methods of the invention.

Abstract translation: 本发明提供用于样品中BK病毒的快速，灵敏和高度特异性核酸（例如基于DNA）检测的方法和组合物。 通常，所述方法涉及检测具有BK病毒基因组的保守区的靶序列的靶核酸。 本发明还包括用于本发明方法的组合物，包括引物，探针和试剂盒。

公开(公告)号：US09745638B2

公开(公告)日：2017-08-29

申请号：US14264462

申请日：2014-04-29

Applicant: Focus Diagnostics, Inc.

Inventor： Fan Chen ,  Lilly I. Kong ,  Jules Chen ,  Mehrdad Jannatipour

IPC: C12P19/34 ,  C12Q1/68 ,  C07H21/02 ,  C07H21/04 ,  C12Q1/70

CPC classification number: C12Q1/701 ,  C12N2710/22011 ,  C12Q2600/158

Abstract: The invention provides methods and compositions for rapid, sensitive, and highly specific nucleic acid-based (e.g., DNA based) detection of a BK virus in a sample. In general, the methods involve detecting a target nucleic acid having a target sequence of a conserved region of BK viral genomes. The invention also features compositions, including primers, probes, and kits, for use in the methods of the invention.