专利检索 ap:("Forschungsverbund Berlin e.V.") AND inv:"Jens Furkert" 第 1 页

1.

发明授权
Antagonists of the thyroid-stimulating hormone receptor (TSHR) 有权

公开(公告)号：US10596168B2

公开(公告)日：2020-03-24

申请号：US16096868

申请日：2017-04-26

申请人： Forschungsverbund Berlin e.V.

发明人： Gerd Krause , Inna Hoyer , Edgar Specker , Jens Furkert , Patrick Marcinkowski , Jens-Peter Von Kries , Martin Neuenschwander , Marc Nazare

IPC分类号： A61K31/429 , A61K31/495 , A61P5/14 , A61P35/00

摘要： Chemical compounds are useful in the treatment of a subject afflicted by a thyroid disease. The compounds exhibit activity as thyroid-stimulating hormone receptor (TSHR) antagonists and can be used in the treatment of hyperthyroidism, Graves' disease, Graves' Ophthalmopathy and thyroid cancer.