公开(公告)号：US20240263240A1

公开(公告)日：2024-08-08

申请号：US18290138

申请日：2022-05-13

Applicant: Foundation Medicine, Inc.

Inventor： Richard Sheng Poe HUANG ,  Brennan DECKER ,  Jeffrey ROSS

IPC: C12Q1/6886 ,  A61K45/06

CPC classification number: C12Q1/6886 ,  A61K45/06 ,  C12Q2600/106 ,  C12Q2600/156

Abstract: Provided herein are methods related to detecting CD274 gene mutations, as well as methods of treatment, uses, and kits related thereto. Detection of CD274 gene mutations can be used to identify individuals that may or may not benefit from an anti-cancer therapy.

公开(公告)号：US20240110230A1

公开(公告)日：2024-04-04

申请号：US18276223

申请日：2022-02-09

Applicant: Foundation Medicine, Inc.

Inventor： Jeffrey ROSS

IPC: C12Q1/6827 ,  A61K45/06 ,  A61P35/00

CPC classification number: C12Q1/6827 ,  A61K45/06 ,  A61P35/00 ,  G01N2800/52

Abstract: The present disclosure provides biomarkers associated with cancers, such as urothelial bladder cancer, non-small cell lung cancer, and renal cell carcinoma, as well as methods, kits and reagents for detecting such biomarkers. The disclosure also provides methods for evaluating, identifying, assessing, and/or treating an individual having a cancer, such as a urothelial bladder cancer, non-small cell lung cancer, and renal cell carcinoma.