专利检索 ap:("Fred Hutchinson Cancer Center" OR "University of Washington") AND inv:"David Koelle" 第 1 页

1.

发明公开
ANTIBODIES THAT BIND THE TUMOR (T) ANTIGEN OF MERKEL CELL POLYOMAVIRUS AND RELATED DIAGNOSTICS 审中-公开

公开(公告)号：US20240131132A1

公开(公告)日：2024-04-25

申请号：US18492705

申请日：2023-10-22

申请人： Fred Hutchinson Cancer Center , University of Washington

发明人： Justin J. Taylor , Denise Galloway , Paul Nghiem , David Koelle , Haroldo Rodriguez , Joseph Carter

IPC分类号： A61K39/00 , A61K45/06 , A61P35/00 , C07K16/28 , G01N33/533 , G01N33/574

CPC分类号： A61K39/001111 , A61K45/06 , A61P35/00 , C07K16/2809 , G01N33/533 , G01N33/57492 , A61K2039/53 , G01N2333/7051

摘要： Antibodies that bind the tumor (T) antigen of the Merkel cell polyomavirus are disclosed. The antibodies can be use used in cell-based immunotherapies, antibody-based therapies, diagnostics, and detection assays, among other uses. Related diagnostics are also described

2.

发明公开
ANTIBODIES THAT BIND THE TUMOR (T) ANTIGEN OF MERKEL CELL POLYOMAVIRUS AND RELATED DIAGNOSTICS 审中-公开

公开(公告)号：US20240226257A9

公开(公告)日：2024-07-11

申请号：US18492705

申请日：2023-10-23

申请人： Fred Hutchinson Cancer Center , University of Washington

发明人： Justin J. Taylor , Denise Galloway , Paul Nghiem , David Koelle , Haroldo Rodriguez , Joseph Carter

IPC分类号： A61K39/00 , A61K45/06 , A61P35/00 , C07K16/28 , G01N33/533 , G01N33/574

CPC分类号： A61K39/001111 , A61K45/06 , A61P35/00 , C07K16/2809 , G01N33/533 , G01N33/57492 , A61K2039/53 , G01N2333/7051

摘要： Antibodies that bind the tumor (T) antigen of the Merkel cell polyomavirus are disclosed. The antibodies can be use used in cell-based immunotherapies, antibody-based therapies, diagnostics, and detection assays, among other uses. Related diagnostics are also described

3.

发明申请
HERPES SIMPLEX VIRUS VACCINE EPITOPES SPECIFICALLY RECOGNIZED BY TISSUE RESIDENT MEMORY T CELLS 审中-公开

公开(公告)号：US20200164060A1

公开(公告)日：2020-05-28

申请号：US16632853

申请日：2018-07-20

申请人： Fred Hutchinson Cancer Research Center , University of Washington

发明人： David Koelle , Anna Wald , Christine Johnston , Christine Posavad , Larry Corey

IPC分类号： A61K39/245 , C12N7/00 , C07K14/005 , C07K14/705 , C07K14/73

摘要： Herpes Simplex Virus type 2 (HSV-2) epitopes bound by CD8 or CD4 tissue resident memory cells at a healed site of HSV-2 infection are disclosed. The HSV-2 epitopes can be used as immunogenic compositions to elicit protective immune responses against HSV-2.