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    Derivatives of 5-(pyridin-3-yl)-1-azabicyclo[3.2.1]octane, their preparation and their therapeutic application
    1.
    发明申请
    Derivatives of 5-(pyridin-3-yl)-1-azabicyclo[3.2.1]octane, their preparation and their therapeutic application 有权
    5-（吡啶-3-基）-1-氮杂双环[3.2.1]辛烷的衍生物及其制备方法及其治疗应用

    公开(公告)号：US20070185137A1

    公开(公告)日：2007-08-09

    申请号：US11696993

    申请日：2007-04-05

    申请人： Frederic GALLI ,  Odile LECLERC ,  Alistair LOCHEAD ,  Alain NEDELEC

    发明人： Frederic GALLI ,  Odile LECLERC ,  Alistair LOCHEAD ,  Alain NEDELEC

    IPC分类号： A61K31/506 ,  A61K31/4439 ,  C07D487/04

    CPC分类号： C07D471/08

    摘要： Compounds complying with the general formula in which R either represents a halogen atom or a phenyl group substituted by one or more groups chosen from halogen atoms and (C1-C6)alkyl, (C1-C6)alkoxy, nitro, amino, trifluoromethyl, cyano, hydroxy, acetyl or methylenedioxy groups, or represents a pyridinyl group, a thienyl group, an indolyl group, or a pyrimidinyl group optionally substituted by one or more (C1-C6)alkoxy groups, where, of the two carbon-carbon bonds represented by one is single and the other may be single or double. The compounds of this invention are useful as therapeutic agents.

    摘要翻译： 符合通式的化合物，其中R代表卤素原子或被一个或多个选自卤素原子和（C 1 -C 6 -C 6）烷基的基团取代的苯基， 烷基，（C 1 -C 6 -C 6）烷氧基，硝基，氨基，三氟甲基，氰基，羟基，乙酰基或亚甲二氧基，或表示吡啶基，噻吩基， 任选被一个或多个（C 1 -C 6 -C 6）烷氧基取代的吲哚基或嘧啶基，其中由以下的两个碳 - 碳键表示： img id =“custom-character-00001”he =“2.79mm”wi =“4.23mm”file =“US20070185137A1-20070809-P00001.TIF”alt =“custom character”img-content =“character”img-format = “tif”/>一个是单个，另一个可以是单个或双重。 本发明的化合物可用作治疗剂。