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公开(公告)号:US5306717A
公开(公告)日:1994-04-26
申请号:US924598
申请日:1992-07-24
申请人: Friedhelm Adam , Walter Durckheimer , Gerd Fischer , Burkhard Mencke , Gerhard Seibert , Dieter Isert , Norbert Klesel
发明人: Friedhelm Adam , Walter Durckheimer , Gerd Fischer , Burkhard Mencke , Gerhard Seibert , Dieter Isert , Norbert Klesel
IPC分类号: A61K20060101 , A61K31/545 , A61K31/546 , A61P31/04 , C07D20060101 , C07D501/00 , C07D501/04 , C07D501/06 , C07D501/22 , C07D501/34 , C07D501/46
CPC分类号: C07D501/34
摘要: Cephalosporin derivatives of the general formula ##STR1## pharmaceutical preparations which are active against bacterial infections and contain such cephem derivatives, processes for the preparation of the cephem derivatives and the pharmaceutical preparations and the use of the cephem derivatives for combating bacterial infections.
摘要翻译: 具有抗细菌感染和含有此类头孢烯衍生物的通式为“IMAGE”+ TR
的药物制剂的头孢菌素衍生物,头孢烯衍生物和药物制剂的制备方法以及头孢烯衍生物用于对抗细菌 感染。 -
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公开(公告)号:US5409918A
公开(公告)日:1995-04-25
申请号:US931505
申请日:1992-08-21
IPC分类号: A61K31/545 , A61K31/546 , A61P31/04 , C07D501/00 , C07D501/34 , C07D501/56 , C07D501/32
CPC分类号: C07D501/00
摘要: Crystalline cephem acid addition salts of the general formula II ##STR1## pharmaceutical preparations effective against bacterial infections which contain such cephem derivatives, processes for the preparation of the cephem derivatives and the pharmaceutical preparations, and the use of the cephem derivatives for combating bacterial infections.
摘要翻译: 具有通式II的结晶头孢酸加成盐对于含有此类头孢烯衍生物的细菌感染药物制剂,制备头孢烯衍生物和药物制剂的方法,以及使用头孢烯 防治细菌感染的衍生物。
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公开(公告)号:US4454129A
公开(公告)日:1984-06-12
申请号:US373790
申请日:1982-04-30
IPC分类号: A61K31/545 , A61K31/546 , A61P31/04 , C07C235/74 , C07D277/36 , C07D501/34 , C07D501/36 , C07D501/46 , C07D501/56
CPC分类号: C07C235/74 , C07D277/36
摘要: What are disclosed are cephem compounds of the formula ##STR1## useful for combating bacterial infections, and methods of making and using the same.
摘要翻译: 所公开的是用于对抗细菌感染的具有式(IMAGE)+ TR< IMAGE>的头孢烯化合物及其制备和使用方法。
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公开(公告)号:US4590267A
公开(公告)日:1986-05-20
申请号:US770406
申请日:1985-08-28
申请人: Karl-Heinz Scheunemann , Burkhard Mencke , Jurgen Blumbach , Walter Durckheimer , Klaus Fleischmann
发明人: Karl-Heinz Scheunemann , Burkhard Mencke , Jurgen Blumbach , Walter Durckheimer , Klaus Fleischmann
IPC分类号: C07D501/00 , A61K31/38 , A61K31/545 , A61K31/546 , A61P31/04 , C07D20060101 , C07D501/12 , C07D501/36 , C07D501/46 , C07D501/56
CPC分类号: C07D501/36
摘要: A crystalline water soluble disodium salt of 7-.beta.-[2-(2-aminothiazol-4-yl)-2-syn-methoximinoacetamido]-3-(5-carboxymethyl-4-methyl-1,3-thiazol-2-ylthiomethyl)ceph-3-em-4-carboxylic acid (cefodizim), or an adduct or solvate thereof with water and/or an organic solvent.
摘要翻译: 7β-[2-(2-氨基噻唑-4-基)-2-顺式 - 邻甲酰氨基乙酰氨基] -3-(5-羧甲基-4-甲基-1,3-噻唑-2 - 硫基甲基)头孢-3-烯-4-羧酸(头孢地嗪)或其与水和/或有机溶剂的加合物或溶剂合物。
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