公开(公告)号：US20250019775A1

公开(公告)日：2025-01-16

申请号：US18900574

申请日：2024-09-27

Applicant: GEN-PROBE INCORPORATED

Inventor： Barbara L. EATON ,  Benjamin GROBARCZYK ,  Samira BARHDADI

IPC: C12Q1/689 ,  C12Q1/6816

Abstract: Disclosed are nucleic acid oligomers, including amplification oligomers and detection probes, for detection of Bordetella pertussis and Bordetella parapertussis nucleic acid. Also disclosed are methods of specific nucleic acid amplification and detection using the disclosed oligomers, as well as corresponding reaction mixtures and kits.

公开(公告)号：US20250034661A1

公开(公告)日：2025-01-30

申请号：US18907406

申请日：2024-10-04

Applicant: GEN-PROBE INCORPORATED

Inventor： Barbara L. EATON ,  Benjamin GROBARCZYK ,  Samira BARHDADI

IPC: C12Q1/689 ,  C12Q1/6816

Abstract: Disclosed are nucleic acid oligomers, including amplification oligomers and detection probes, for detection of Bordetella pertussis and Bordetella parapertussis nucleic acid. Also disclosed are methods of specific nucleic acid amplification and detection using the disclosed oligomers, as well as corresponding reaction mixtures and kits.

公开(公告)号：US20210269854A1

公开(公告)日：2021-09-02

申请号：US17255500

申请日：2019-06-14

Applicant: GEN-PROBE INCORPORATED

Inventor： Matthias JOST ,  Barbara L. EATON ,  Ankur SHAH

IPC: C12Q1/6806 ,  C12N15/10 ,  C12Q1/689

Abstract: Method of preparing a biological sample appropriate for use in a subsequent in vitro nucleic acid amplification reaction. A biological sample is combined with an alkaline composition that lyses cells and denatures DNA to create a first liquid composition. The first liquid composition is then mixed with a buffer, a detergent, and a solid support that captures DNA to create a second liquid composition. The buffer, detergent, and solid support can be delivered as components of a single reagent. Captured DNA strands can be used as templates in subsequently performed nucleic acid amplification and detection reactions with improved sensitivity.

公开(公告)号：US20190002993A1

公开(公告)日：2019-01-03

申请号：US16065461

申请日：2017-01-04

Applicant: GEN-PROBE INCORPORATED

Inventor： Angela S. HUDSON ,  Damon K. GETMAN ,  Alice JIANG ,  Barbara L. EATON

IPC: C12Q1/6895 ,  C12Q1/6806 ,  C12Q1/686 ,  C12Q1/689

Abstract: Disclosed are methods utilizing specific amplification of Candida sp. target nucleic acid for detecting the presence or absence of Candida sp. in a sample. Also disclosed are corresponding oligomers, including amplification oligomers, capture probes and detection probes, and combinations thereof, as well as corresponding reaction mixtures and kits.