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1.发明申请METHODS OF PROGNOSING, DIAGNOSING AND TREATING IDIOPATHIC PULMONARY FIBROSIS 审中-公开预防，诊断和治疗特发性肺动脉硬化症的方法公开(公告)号：US20160230226A1
公开(公告)日：2016-08-11
申请号：US14493649
申请日：2014-09-23
申请人： GENENTECH, INC.
发明人： Alexander R. Abbas , Joseph R. Arron , Sanjay Chandriani , Guiquan Jia , Nicholas J.I. Lewin-Koh , Daryle DePianto
CPC分类号： C12Q1/6883 , A61K38/00 , A61K2039/505 , A61K2039/54 , A61K2039/545 , C07K16/244 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C12Q2600/118 , C12Q2600/158 , G01N33/6893 , G01N2333/521 , G01N2333/775 , G01N2333/96494 , G01N2800/12 , G01N2800/52
摘要： Compositions, kits and methods for assessing the prognosis of idiopathic pulmonary fibrosis in patients are provided. In addition, compositions, kits and methods for diagnosing subtypes of idiopathic pulmonary fibrosis are provided. Also provided are methods for treating idiopathic pulmonary fibrosis.
摘要翻译： 提供了用于评估患者特发性肺纤维化预后的组合物，试剂盒和方法。 此外，提供了用于诊断特发性肺纤维化亚型的组合物，试剂盒和方法。 还提供了治疗特发性肺纤维化的方法。
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公开(公告)号：US20140179620A1
公开(公告)日：2014-06-26
申请号：US13964861
申请日：2013-08-12
申请人： GENENTECH, INC.
发明人： Alexander R. Abbas , Hilary Clark , Lauri Diehl , Charles Lees , Colin L. Noble , Jack Satsangi
IPC分类号： C12Q1/68 , G01N33/564
CPC分类号： G01N33/564 , A61K31/56 , A61K31/606 , C12Q1/6883 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/156 , C12Q2600/158 , C12Q2600/172
摘要： The present invention relates to methods of gene expression profiling for inflammatory bowel disease pathogenesis, in which the differential expression in a test sample from a mammalian subject of one or more IBD markers relative to a control is determined, wherein the differential expression in the test sample is indicative of an IBD in the mammalian subject from which the test sample was obtained.
摘要翻译： 本发明涉及炎症性肠病发病机理的基因表达谱的方法，其中测定来自一个或多个IBD标记物的哺乳动物受试者相对于对照的测试样品中的差异表达，其中测试样品中的差异表达 指示获得测试样品的哺乳动物受试者中的IBD。
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公开(公告)号：US20140154275A1
公开(公告)日：2014-06-05
申请号：US14020628
申请日：2013-09-06
申请人： GENENTECH, INC.
发明人： Alexander R. Abbas , Hilary Clark , Lauri Diehl , Charles Lees , Colin L. Noble , Jack Satsangi
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/158
摘要： The present invention relates to methods of gene expression profiling for inflammatory bowel disease pathogenesis, in which the differential expression in a test sample from a mammalian subject of one or more IBD markers relative to a control is determined, wherein the differential expression in the test sample is indicative of an IBD in the mammalian subject from which the test sample was obtained.
摘要翻译： 本发明涉及炎症性肠病发病机理的基因表达谱的方法，其中测定来自一个或多个IBD标记物的哺乳动物受试者相对于对照的测试样品中的差异表达，其中测试样品中的差异表达 指示获得测试样品的哺乳动物受试者中的IBD。
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