公开(公告)号：US20160297767A1

公开(公告)日：2016-10-13

申请号：US15186246

申请日：2016-06-17

Applicant: GENENTECH, INC.

Inventor： Nicholas D. Smith ,  Mehmet Kahraman ,  Steven P. Govek ,  Johnny Y. Nagasawa ,  Andiliy G. Lai ,  Jackaline D. Julien ,  Mark R. Herbert ,  Celine Bonnefous ,  Karensa L. Douglas

IPC: C07D231/56 ,  C07C215/10

CPC classification number: C07D231/56 ,  A61K31/416 ,  A61K31/7056 ,  A61K31/7068 ,  A61K31/7072 ,  A61K31/7076 ,  A61K31/708 ,  A61K31/7105 ,  C07C215/10 ,  C07D209/08 ,  C07D215/227 ,  C07D217/24 ,  C07D249/18 ,  C07D265/18 ,  C07D277/68 ,  C07D279/16 ,  C07D401/10 ,  C07D401/12 ,  C07D403/10 ,  C07D409/10 ,  C07D413/10 ,  C07D417/10 ,  C07D471/04 ,  C07D495/04

Abstract: Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such estrogen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.