公开(公告)号：US20210132085A1

公开(公告)日：2021-05-06

申请号：US17150504

申请日：2021-01-15

Applicant: GENENTECH, INC. ,  Roche Diagnostics Operations, Inc.

Inventor： Tobias Bittner ,  Johann Karl ,  Valeria Lifke ,  Verena Steffen ,  Martina Jocham

IPC: G01N33/68 ,  G01N33/577

Abstract: The present disclosure relates to identifying an individual as having or being at risk of developing an amyloid-positive dementia based on marker molecules amyloid β40 (Aβ40), amyloid β42 (Aβ42) and total Tau (tTau), the use of the marker molecules for the identification of an individual having or being at risk of developing an amyloid-positive dementia and a method for detecting an individual with an increased value for the combination of the marker molecules.