公开(公告)号：US20180344880A1

公开(公告)日：2018-12-06

申请号：US16102368

申请日：2018-08-13

Applicant: GENERAL ELECTRIC COMPANY

Inventor： Matthew David BUTTS ,  Jason William CASTLE ,  Andrew Soliz TORRES ,  Jeannette Christine ROBERTS ,  Binil Itty Ipe KANDAPALLIL

IPC: A61K49/22 ,  A61K9/50 ,  A61K9/00

Abstract: The present disclosure relates to a composition of albumin microbubbles to which are bound one or more moieties that exhibit a binding preference for the albumin microbubbles relative to free, native HSA. Production of the albumin microbubble composition and use of the albumin microbubble composition in ultrasound mediated delivery of therapeutic or diagnostic agents is also discussed.

公开(公告)号：US20200345869A1

公开(公告)日：2020-11-05

申请号：US16935998

申请日：2020-07-22

Applicant: General Electric Company

Inventor： Matthew David BUTTS ,  Jason William CASTLE ,  Andrew Soliz TORRES ,  Jeannette Christine ROBERTS ,  Binil Itty Ipe KANDAPALLIL

IPC: A61K49/22 ,  A61K9/50 ,  A61K9/00

Abstract: The present disclosure relates to a composition of albumin microbubbles to which are bound one or more moieties that exhibit a binding preference for the albumin microbubbles relative to free, native HSA. Production of the albumin microbubble composition and use of the albumin microbubble composition in ultrasound mediated delivery of therapeutic or diagnostic agents is also discussed.