公开(公告)号：US20180344880A1

公开(公告)日：2018-12-06

申请号：US16102368

申请日：2018-08-13

Applicant: GENERAL ELECTRIC COMPANY

Inventor： Matthew David BUTTS ,  Jason William CASTLE ,  Andrew Soliz TORRES ,  Jeannette Christine ROBERTS ,  Binil Itty Ipe KANDAPALLIL

IPC: A61K49/22 ,  A61K9/50 ,  A61K9/00

Abstract: The present disclosure relates to a composition of albumin microbubbles to which are bound one or more moieties that exhibit a binding preference for the albumin microbubbles relative to free, native HSA. Production of the albumin microbubble composition and use of the albumin microbubble composition in ultrasound mediated delivery of therapeutic or diagnostic agents is also discussed.

公开(公告)号：US20200185118A1

公开(公告)日：2020-06-11

申请号：US16791344

申请日：2020-02-14

Applicant: GENERAL ELECTRIC COMPANY ,  MEDI-PHYSICS INC.

Inventor： Matthew David BUTTS ,  Charles E. SHANKS

IPC: G21G4/06 ,  G21G1/02 ,  G21G1/00 ,  G21G4/08

Abstract: An equatorial anthropic radiation source and a method of making an equatorial anthropic radiation source are described. The radiation source is useful in diagnostic imaging applications in healthcare or other industries (e.g. computerized three-dimensional segmental imaging; Crompton scattering imaging techniques; radiation detector check and calibration, in particular CdZnTe detectors commonly used in medical imaging).

公开(公告)号：US20200345869A1

公开(公告)日：2020-11-05

申请号：US16935998

申请日：2020-07-22

Applicant: General Electric Company

Inventor： Matthew David BUTTS ,  Jason William CASTLE ,  Andrew Soliz TORRES ,  Jeannette Christine ROBERTS ,  Binil Itty Ipe KANDAPALLIL

IPC: A61K49/22 ,  A61K9/50 ,  A61K9/00

Abstract: The present disclosure relates to a composition of albumin microbubbles to which are bound one or more moieties that exhibit a binding preference for the albumin microbubbles relative to free, native HSA. Production of the albumin microbubble composition and use of the albumin microbubble composition in ultrasound mediated delivery of therapeutic or diagnostic agents is also discussed.

公开(公告)号：US20190292448A1

公开(公告)日：2019-09-26

申请号：US16348763

申请日：2017-11-15

Applicant: GENERAL ELECTRIC COMPANY

Inventor： Digamber Gurudas POROB ,  Prasanth Kumar NAMMALWAR ,  Srinidhi RAMACHANDRA ,  Matthew David BUTTS ,  James Edward MURPHY

IPC: C09K11/02 ,  C09K11/61 ,  H01L33/50

Abstract: A process for coating a phosphor of formula I: Ax[MFy]:Mn4+ includes combining the phosphor of formula I in particulate form with a first solution including a compound of formula II: Ax[MFy] to form a suspension and combining a second solution with the suspension, the second solution including a precursor including an element selected from the group consisting of calcium, strontium, magnesium, yittrium, barium, scandium, lanthanum, and combinations thereof. A population of particles having a core including a phosphor of formula I and a manganese-free composite coating disposed on the core, and a lighting apparatus (10) including the population of particles are also presented.