公开(公告)号：US20150310640A1

公开(公告)日：2015-10-29

申请号：US14261623

申请日：2014-04-25

Applicant: General Electric Company

Inventor： Christopher Judson Hardy ,  Luca Marinelli ,  Marion Irene Menzel ,  Ek Tsoon Tan ,  Jonathan Immanuel Sperl

IPC: G06T11/00 ,  G06T7/00

CPC classification number: G06T11/006 ,  G01R33/4826 ,  G01R33/5611 ,  G01R33/56341 ,  G06T7/0012 ,  G06T2207/10088 ,  G06T2207/20056

Abstract: A method of compressed sensing for multi-shell magnetic resonance imaging includes obtaining magnetic resonance imaging data, the data being sampled along multi-shell spherical coordinates, the spherical coordinates coincident with a plurality of spokes that converge at an origin, constructing a symmetric shell for each respective sampled multi-shell to create a combined set of data, performing a three-dimensional Fourier transform on the combined set of data to reconstruct an image, and de-noising the reconstructed image by iteratively applying a sparsifying transform on non-sampled data points of neighboring shells. The method can also include randomly under-sampling the imaging data to create missing data points. A system configured to implement the method and a non-transitory computer readable medium are also disclosed.

Abstract translation: 一种用于多壳磁共振成像的压缩感测方法包括：获得磁共振成像数据，所述数据沿着多壳球面坐标进行采样，所述球面坐标与在原点收敛的多个辐条重合，构成对称壳体 每个相应的采样多壳以产生一组组合数据，对该组合数据进行三维傅里叶变换以重构图像，并通过对非采样数据迭代地应用稀疏变换来对重构图像进行去噪 相邻炮弹点。 该方法还可以包括随机对取样数据进行低采样以创建丢失的数据点。 还公开了一种被配置为实现该方法的系统和一种非暂时计算机可读介质。

公开(公告)号：US20160334489A1

公开(公告)日：2016-11-17

申请号：US14711650

申请日：2015-05-13

Applicant: General Electric Company

Inventor： Jonathan Immanuel Sperl ,  Christopher Judson Hardy ,  Luca Marinelli ,  Marion Irene Menzel ,  Ek Tsoon Tan

IPC: G01R33/563 ,  G01R33/56 ,  G01R33/561 ,  G01R33/385

CPC classification number: G01R33/56341 ,  G01R33/5608

Abstract: A magnetic resonance imaging method includes generating spatially resolved fiber orientation distributions (FODs) from magnetic resonance signals acquired from a patient tissue using a plurality of diffusion encodings, each acquired magnetic resonance signal corresponding to one of the diffusion encodings and being representative of a three-dimensional distribution of displacement of magnetic spins of gyromagnetic nuclei present in each imaging voxel. Generating the spatially resolved FODs includes performing generalized spherical deconvolution using the acquired magnetic resonance signals and a modeled tissue response matrix (TRM) to reconstruct the spatially resolved FODs. The method also includes using the spatially resolved FODs to generate a representation of fibrous tissue within the patient tissue.

Abstract translation: 磁共振成像方法包括使用多个扩散编码从从患者组织获取的磁共振信号产生空间分辨纤维取向分布（FOD），每个获得的磁共振信号对应于一个扩散编码，并且代表三维 每个成像体素中存在的回旋磁核的磁自旋的位移的尺寸分布。 生成空间分辨的FOD包括使用获取的磁共振信号和建模的组织响应矩阵（TRM）来执行广义的球形去卷积以重构空间分辨的FOD。 该方法还包括使用空间分辨的FOD来产生患者组织内的纤维组织的表示。

公开(公告)号：US08908951B2

公开(公告)日：2014-12-09

申请号：US13728871

申请日：2012-12-27

Applicant: General Electric Company

Inventor： Marion Irene Menzel ,  Christopher Judson Hardy ,  Kevin Franklin King ,  Luca Marinelli ,  Ek Tsoon Tan ,  Jonathan Immanuel Sperl

IPC: G06K9/00 ,  G06T7/00

CPC classification number: G01R33/56341

Abstract: A magnetic resonance (MR) imaging method includes acquiring MR signals having phase and magnitude at q-space locations using a diffusion sensitizing pulse sequence performed on a tissue of interest, wherein the acquired signals each include a set of complex Fourier encodings representing a three-dimensional displacement distribution of the spins in a q-space location. The signals each include information relating to coherent motion and incoherent motion in the q-space location. The method also includes determining a contribution by coherent motion to the phase of the acquired MR signals; removing the phase contribution attributable to coherent motion from the acquired MR signals to produce a complex data set for each q-space location and an image of velocity components for each q-space location; and producing a three-dimensional velocity image from the image of the velocity components.

Abstract translation: 磁共振（MR）成像方法包括使用在感兴趣的组织上执行的扩散增感脉冲序列获取在q空间位置具有相位和幅度的MR信号，其中所获取的信号各自包括一组代表三维空间的复数傅里叶编码， 在q空间位置的自旋的三维位移分布。 每个信号包括与q空间位置中的相干运动和非相干运动有关的信息。 该方法还包括通过相干运动确定所获取的MR信号的相位的贡献; 从所获取的MR信号去除归因于相干运动的相位贡献，以产生用于每个q空间位置的复数据集合和用于每个q空间位置的速度分量的图像; 并根据速度分量的图像产生三维速度图像。

公开(公告)号：US09720063B2

公开(公告)日：2017-08-01

申请号：US13718119

申请日：2012-12-18

Applicant: General Electric Company

Inventor： Jonathan Immanuel Sperl ,  Christopher Judson Hardy ,  Luca Marinelli ,  Ek Tsoon Tan ,  Kevin Franklin King ,  Marion Irene Menzel

IPC: G01R33/563

CPC classification number: G01R33/56341

Abstract: Systems and methods for generating a magnetic resonance (MR) image of a tissue are provided. A method includes acquiring MR raw data. The MR raw data corresponds to MR signals obtained at undersampled q-space locations for a plurality of q-space locations that is less than an entirety of the q-space locations and the MR signals at the q-space locations represent the three dimensional displacement distribution of the spins in the imaging voxel. The method also includes performing a joint image reconstruction technique on the MR raw data to exploit structural correlations in the MR signals to obtain a series of accelerated MR images and performing, for each image pixel in each accelerated MR image of the series of accelerated MR images, a compressed sensing reconstruction technique to exploit q-space signal sparsity to identify a plurality of diffusion maps.

公开(公告)号：US20140167753A1

公开(公告)日：2014-06-19

申请号：US13718119

申请日：2012-12-18

Applicant: GENERAL ELECTRIC COMPANY

Inventor： Jonathan Immanuel Sperl ,  Christopher Judson Hardy ,  Luca Marinelli ,  Ek Tsoon Tan ,  Kevin Franklin King ,  Marion Irene Menzel

IPC: G01R33/48

CPC classification number: G01R33/56341

Abstract: Systems and methods for generating a magnetic resonance (MR) image of a tissue are provided. A method includes acquiring MR raw data. The MR raw data corresponds to MR signals obtained at undersampled q-space locations for a plurality of q-space locations that is less than an entirety of the q-space locations and the MR signals at the q-space locations represent the three dimensional displacement distribution of the spins in the imaging voxel. The method also includes performing a joint image reconstruction technique on the MR raw data to exploit structural correlations in the MR signals to obtain a series of accelerated MR images and performing, for each image pixel in each accelerated MR image of the series of accelerated MR images, a compressed sensing reconstruction technique to exploit q-space signal sparsity to identify a plurality of diffusion maps.

Abstract translation: 提供了用于产生组织的磁共振（MR）图像的系统和方法。 一种方法包括获取MR原始数据。 MR原始数据对应于在低于q空间位置的整体的多个q空间位置处在欠采样q空间位置处获得的MR信号，并且在q空间位置处的MR信号表示三维位移 旋转成像体素的分布。 该方法还包括对MR原始数据执行联合图像重建技术以利用MR信号中的结构相关性，以获得一系列加速MR图像，并针对一系列加速MR图像的每个加速MR图像中的每个图像像素执行 ，一种利用q空间信号稀疏度来识别多个扩散图的压缩感测重建技术。

公开(公告)号：US10324154B2

公开(公告)日：2019-06-18

申请号：US14711650

申请日：2015-05-13

Applicant: General Electric Company

Inventor： Jonathan Immanuel Sperl ,  Christopher Judson Hardy ,  Luca Marinelli ,  Marion Irene Menzel ,  Ek Tsoon Tan

IPC: G01R33/56 ,  G01R33/563

Abstract: A magnetic resonance imaging method includes generating spatially resolved fiber orientation distributions (FODs) from magnetic resonance signals acquired from a patient tissue using a plurality of diffusion encodings, each acquired magnetic resonance signal corresponding to one of the diffusion encodings and being representative of a three-dimensional distribution of displacement of magnetic spins of gyromagnetic nuclei present in each imaging voxel. Generating the spatially resolved FODs includes performing generalized spherical deconvolution using the acquired magnetic resonance signals and a modeled tissue response matrix (TRM) to reconstruct the spatially resolved FODs. The method also includes using the spatially resolved FODs to generate a representation of fibrous tissue within the patient tissue.

公开(公告)号：US09208587B2

公开(公告)日：2015-12-08

申请号：US14261623

申请日：2014-04-25

Applicant: General Electric Company

Inventor： Christopher Judson Hardy ,  Luca Marinelli ,  Marion Irene Menzel ,  Ek Tsoon Tan ,  Jonathan Immanuel Sperl

IPC: G06K9/00 ,  G06T11/00 ,  G06T7/00

CPC classification number: G06T11/006 ,  G01R33/4826 ,  G01R33/5611 ,  G01R33/56341 ,  G06T7/0012 ,  G06T2207/10088 ,  G06T2207/20056

Abstract: A method of compressed sensing for multi-shell magnetic resonance imaging includes obtaining magnetic resonance imaging data, the data being sampled along multi-shell spherical coordinates, the spherical coordinates coincident with a plurality of spokes that converge at an origin, constructing a symmetric shell for each respective sampled multi-shell to create a combined set of data, performing a three-dimensional Fourier transform on the combined set of data to reconstruct an image, and de-noising the reconstructed image by iteratively applying a sparsifying transform on non-sampled data points of neighboring shells. The method can also include randomly under-sampling the imaging data to create missing data points. A system configured to implement the method and a non-transitory computer readable medium are also disclosed.

Abstract translation: 一种用于多壳磁共振成像的压缩感测方法包括：获得磁共振成像数据，所述数据沿着多壳球面坐标进行采样，所述球面坐标与在原点收敛的多个辐条重合，构成对称壳体 每个相应的采样多壳以产生一组组合数据，对该组合数据进行三维傅里叶变换以重构图像，并通过对非采样数据迭代地应用稀疏变换来对重构图像进行去噪 相邻炮弹点。 该方法还可以包括随机对取样数据进行低采样以创建丢失的数据点。 还公开了一种被配置为实现该方法的系统和一种非暂时计算机可读介质。

公开(公告)号：US20140185894A1

公开(公告)日：2014-07-03

申请号：US13728871

申请日：2012-12-27

Applicant: GENERAL ELECTRIC COMPANY

Inventor： Marion Irene Menzel ,  Christopher Judson Hardy ,  Kevin Franklin King ,  Luca Marinelli ,  Ek Tsoon Tan ,  Jonathan Immanuel Sperl

IPC: G06T7/00

CPC classification number: G01R33/56341

Abstract: A magnetic resonance (MR) imaging method includes acquiring MR signals having phase and magnitude at q-space locations using a diffusion sensitizing pulse sequence performed on a tissue of interest, wherein the acquired signals each include a set of complex Fourier encodings representing a three-dimensional displacement distribution of the spins in a q-space location. The signals each include information relating to coherent motion and incoherent motion in the q-space location. The method also includes determining a contribution by coherent motion to the phase of the acquired MR signals; removing the phase contribution attributable to coherent motion from the acquired MR signals to produce a complex data set for each q-space location and an image of velocity components for each q-space location; and producing a three-dimensional velocity image from the image of the velocity components.

Abstract translation: 磁共振（MR）成像方法包括使用在感兴趣的组织上执行的扩散增感脉冲序列获取在q空间位置具有相位和幅度的MR信号，其中所获取的信号各自包括一组代表三维空间的复数傅里叶编码， 在q空间位置的自旋的三维位移分布。 每个信号包括与q空间位置中的相干运动和非相干运动有关的信息。 该方法还包括通过相干运动确定所获取的MR信号的相位的贡献; 从所获取的MR信号去除归因于相干运动的相位贡献，以产生用于每个q空间位置的复数数据集和用于每个q空间位置的速度分量的图像; 并根据速度分量的图像产生三维速度图像。