公开(公告)号：US20200255911A1

公开(公告)日：2020-08-13

申请号：US16800292

申请日：2020-02-25

申请人： GENOMIC HEALTH, INC.

发明人： Steven SHAK ,  Frederick L. BAEHNER ,  Tara MADDALA ,  Mark LEE ,  Robert J. PELHAM ,  Wayne COWENS ,  Diana CHERBAVAZ ,  Michael C. KIEFER ,  Michael CRAGER ,  Audrey GODDARD ,  Joffre B. BAKER

IPC分类号： C12Q1/6886

摘要： Molecular assays that involve measurement of expression levels of prognostic biomarkers, or co-expressed biomarkers, from a biological sample obtained from a prostate cancer patient, and analysis of the measured expression levels to provide information concerning the likely prognosis for said patient, and likelihood that said patient will have a recurrence of prostate cancer, or to classify the tumor by likelihood of clinical outcome or TMPRSS2 fusion status, are provided herein.

公开(公告)号：US20190249260A1

公开(公告)日：2019-08-15

申请号：US16282540

申请日：2019-02-22

申请人： GENOMIC HEALTH, INC.

发明人： Steven SHAK ,  Frederick L. BAEHNER ,  Tara MADDALA ,  Mark LEE ,  Robert J. PELHAM ,  Wayne COWENS ,  Diana CHERBAVAZ ,  Michael C. KIEFER ,  Michael CRAGER ,  Audrey GODDARD ,  Joffre B. BAKER

IPC分类号： C12Q1/6886

CPC分类号： C12Q1/6886 ,  C12Q2600/118 ,  C12Q2600/158 ,  C12Q2600/178

摘要： Molecular assays that involve measurement of expression levels of prognostic biomarkers, or co-expressed biomarkers, from a biological sample obtained from a prostate cancer patient, and analysis of the measured expression levels to provide information concerning the likely prognosis for said patient, and likelihood that said patient will have a recurrence of prostate cancer, or to classify the tumor by likelihood of clinical outcome or TMPRSS2 fusion status, are provided herein.

公开(公告)号：US20160097105A1

公开(公告)日：2016-04-07

申请号：US14887605

申请日：2015-10-20

申请人： GENOMIC HEALTH, INC.

发明人： Steven SHAK ,  Frederick L. BAEHNER ,  Tara MADDALA ,  Mark LEE ,  Robert J. PELHAM ,  Wayne COWENS ,  Diana CHERBAVAZ ,  Michael C. KIEFER ,  Michael CRAGER ,  Audrey GODDARD ,  Joffre B. BAKER

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6886 ,  C12Q2600/118 ,  C12Q2600/158 ,  C12Q2600/178 ,  G06F19/00

摘要： Molecular assays that involve measurement of expression levels of prognostic biomarkers, or co-expressed biomarkers, from a biological sample obtained from a prostate cancer patient, and analysis of the measured expression levels to provide information concerning the likely prognosis for said patient, and likelihood that said patient will have a recurrence of prostate cancer, or to classify the tumor by likelihood of clinical outcome or TMPRSS2 fusion status, are provided herein.

摘要翻译： 涉及从前列腺癌患者获得的生物样品中测量预后生物标志物或共表达生物标志物的表达水平的分子测定，以及测量的表达水平的分析以提供关于所述患者的可能预后的信息，以及可能性 所述患者将具有前列腺癌的复发，或通过临床结果或TMPRSS2融合状态的可能性来分类肿瘤。