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公开(公告)号：US20210062275A1
公开(公告)日：2021-03-04
申请号：US17018143
申请日：2020-09-11
Applicant: GENOMIC HEALTH, INC.
Inventor： Joffre B. BAKER , Maureen T. CRONIN , Francois COLLIN , Mei-Lan LIU
IPC: C12Q1/6886 , G16B25/00
Abstract: The present invention provides methods to determine the prognosis and appropriate treatment for patients diagnosed with cancer, based on the expression levels of one or more biomarkers. More particularly, the invention relates to the identification of genes, or sets of genes, able to distinguish breast cancer patients with a good clinical prognosis from those with a bad clinical prognosis. The invention further provides methods for providing a personalized genomics report for a cancer patient. The inventions also relates to computer systems and software for data analysis using the prognostic and statistical methods disclosed herein.
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Patent Agency Ranking
公开(公告)号：US20190256923A1
公开(公告)日：2019-08-22
申请号：US16250179
申请日：2019-01-17
Applicant: GENOMIC HEALTH, INC.
Inventor： Joffre B. BAKER , Dominick SINICROPI , Robert J. PELHAM , Michael R. CRAGER , Francois COLLIN , James C. STEPHANS , Mei-Lan LIU , John D. MORLAN , Kunbin QU
IPC: C12Q1/6886 , G16B20/00 , C12Q1/686 , G01N33/574
Abstract: The present invention relates to biomarkers associated with breast cancer prognosis. These biomarkers include coding transcripts and their expression products, as well as non-coding transcripts, and are useful for predicting the likelihood of breast cancer recurrence in a breast cancer patient. The present invention also relates to a novel method of identifying intergenic sequences that correlate with a clinical outcome.
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公开(公告)号：US20160222463A1
公开(公告)日：2016-08-04
申请号：US15011206
申请日：2016-01-29
Applicant: GENOMIC HEALTH, INC.
Inventor： Joffre B. BAKER , Dominick S. SINICROPI , Robert J. PELHAM , Michael R. CRAGER , Francois COLLIN , James C. STEPHANS , Mei-Lan LIU , John D. MORLAN , Kunbin QU
IPC: C12Q1/68
CPC classification number: C12Q1/6886 , C12Q1/686 , C12Q2600/118 , C12Q2600/158 , C12Q2600/178 , G01N33/57415 , G01N2800/54 , G01N2800/56 , G01N2800/60 , G16B20/00
Abstract: The present invention relates to biomarkers associated with breast cancer prognosis. These biomarkers include coding transcripts and their expression products, as well as non-coding transcripts, and are useful for predicting the likelihood of breast cancer recurrence in a breast cancer patient, The present invention also relates to a novel method of identifying intergenic sequences that correlate with a clinical outcome.
Abstract translation: 本发明涉及与乳腺癌预后相关的生物标志物。 这些生物标志物包括编码转录物及其表达产物，以及非编码转录物，并且可用于预测乳腺癌患者乳腺癌复发的可能性。本发明还涉及一种鉴定与之相关的基因间序列的新方法 具有临床结果。
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公开(公告)号：US20200263257A1
公开(公告)日：2020-08-20
申请号：US16784696
申请日：2020-02-07
Applicant: GENOMIC HEALTH, INC.
Inventor： Joffre B. BAKER , Dominick SINICROPI , Robert J. PELHAM , Michael R. CRAGER , Francois COLLIN , James C. STEPHANS , Mei-Lan LIU , John D. MORLAN , Kunbin QU
IPC: C12Q1/6886 , G01N33/574 , C12Q1/686 , G16B20/00
Abstract: The present invention relates to biomarkers associated with breast cancer prognosis. These biomarkers include coding transcripts and their expression products, as well as non-coding transcripts, and are useful for predicting the likelihood of breast cancer recurrence in a breast cancer patient. The present invention also relates to a novel method of identifying intergenic sequences that correlate with a clinical outcome.
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公开(公告)号：US20190241967A1
公开(公告)日：2019-08-08
申请号：US16243207
申请日：2019-01-09
Applicant: GENOMIC HEALTH, INC.
Inventor： Joffre B. BAKER , Maureen T. CRONIN , Francois COLLIN , Mei-Lan LIU
IPC: C12Q1/6886 , G16B25/00
CPC classification number: C12Q1/6886 , C12Q2600/106 , C12Q2600/118 , C12Q2600/156 , C12Q2600/158 , G16B25/00
Abstract: The present invention provides methods to determine the prognosis and appropriate treatment for patients diagnosed with cancer, based on the expression levels of one or more biomarkers. More particularly, the invention relates to the identification of genes, or sets of genes, able to distinguish breast cancer patients with a good clinical prognosis from those with a bad clinical prognosis. The invention further provides methods for providing a personalized genomics report for a cancer patient. The inventions also relates to computer systems and software for data analysis using the prognostic and statistical methods disclosed herein.
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公开(公告)号：US20170211154A1
公开(公告)日：2017-07-27
申请号：US15423977
申请日：2017-02-03
Applicant: GENOMIC HEALTH, INC.
Inventor： Joffre B. BAKER , Maureen T. CRONIN , Francois COLLIN , Mei-Lan LIU
Abstract: The present invention provides methods to determine the prognosis and appropriate treatment for patients diagnosed with cancer, based on the expression levels of one or more biomarkers. More particularly, the invention relates to the identification of genes, or sets of genes, able to distinguish breast cancer patients with a good clinical prognosis from those with a bad clinical prognosis. The invention further provides methods for providing a personalized genomics report for a cancer patient. The inventions also relates to computer systems and software for data analysis using the prognostic and statistical methods disclosed herein.
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