公开(公告)号：US20200263257A1

公开(公告)日：2020-08-20

申请号：US16784696

申请日：2020-02-07

Applicant: GENOMIC HEALTH, INC.

Inventor： Joffre B. BAKER ,  Dominick SINICROPI ,  Robert J. PELHAM ,  Michael R. CRAGER ,  Francois COLLIN ,  James C. STEPHANS ,  Mei-Lan LIU ,  John D. MORLAN ,  Kunbin QU

IPC: C12Q1/6886 ,  G01N33/574 ,  C12Q1/686 ,  G16B20/00

Abstract: The present invention relates to biomarkers associated with breast cancer prognosis. These biomarkers include coding transcripts and their expression products, as well as non-coding transcripts, and are useful for predicting the likelihood of breast cancer recurrence in a breast cancer patient. The present invention also relates to a novel method of identifying intergenic sequences that correlate with a clinical outcome.

公开(公告)号：US20190256923A1

公开(公告)日：2019-08-22

申请号：US16250179

申请日：2019-01-17

Applicant: GENOMIC HEALTH, INC.

Inventor： Joffre B. BAKER ,  Dominick SINICROPI ,  Robert J. PELHAM ,  Michael R. CRAGER ,  Francois COLLIN ,  James C. STEPHANS ,  Mei-Lan LIU ,  John D. MORLAN ,  Kunbin QU

IPC: C12Q1/6886 ,  G16B20/00 ,  C12Q1/686 ,  G01N33/574

Abstract: The present invention relates to biomarkers associated with breast cancer prognosis. These biomarkers include coding transcripts and their expression products, as well as non-coding transcripts, and are useful for predicting the likelihood of breast cancer recurrence in a breast cancer patient. The present invention also relates to a novel method of identifying intergenic sequences that correlate with a clinical outcome.

公开(公告)号：US20160222463A1

公开(公告)日：2016-08-04

申请号：US15011206

申请日：2016-01-29

Applicant: GENOMIC HEALTH, INC.

Inventor： Joffre B. BAKER ,  Dominick S. SINICROPI ,  Robert J. PELHAM ,  Michael R. CRAGER ,  Francois COLLIN ,  James C. STEPHANS ,  Mei-Lan LIU ,  John D. MORLAN ,  Kunbin QU

IPC: C12Q1/68

CPC classification number: C12Q1/6886 ,  C12Q1/686 ,  C12Q2600/118 ,  C12Q2600/158 ,  C12Q2600/178 ,  G01N33/57415 ,  G01N2800/54 ,  G01N2800/56 ,  G01N2800/60 ,  G16B20/00

Abstract: The present invention relates to biomarkers associated with breast cancer prognosis. These biomarkers include coding transcripts and their expression products, as well as non-coding transcripts, and are useful for predicting the likelihood of breast cancer recurrence in a breast cancer patient, The present invention also relates to a novel method of identifying intergenic sequences that correlate with a clinical outcome.

Abstract translation: 本发明涉及与乳腺癌预后相关的生物标志物。 这些生物标志物包括编码转录物及其表达产物，以及非编码转录物，并且可用于预测乳腺癌患者乳腺癌复发的可能性。本发明还涉及一种鉴定与之相关的基因间序列的新方法 具有临床结果。