专利检索 ap:("GEORG-AUGUST-UNIVERSITÄT GÖTTINGEN STIFTUNG ÖFFENTLICHEN RECHTS, UNIVERSITÄTSMEDIZIN" OR "TEVA PHARMACEUTICAL INDUSTRIES LTD.") AND inv:"Wolfgang BRÜCK" 第 1 页

1.

发明申请
QUINOLINE DERIVATIVES FOR USE IN TREATING LEUKODYSTROPHY AND TREATMENT METHOD 审中-公开

公开(公告)号：US20180250284A1

公开(公告)日：2018-09-06

申请号：US15758098

申请日：2016-09-08

申请人： GEORG-AUGUST-UNIVERSITÄT GÖTTINGEN STIFTUNG ÖFFENTLICHEN RECHTS, UNIVERSITÄTSMEDIZIN , TEVA PHARMACEUTICAL INDUSTRIES LTD.

发明人： Volker KNAPPERTZ , Michael HAYDEN , Wolfgang BRÜCK , Stefan NESSLER

IPC分类号： A61K31/4704 , A61K9/00

CPC分类号： A61K31/4704 , A61K9/0053 , C07D217/26

摘要： The present invention relates in a first aspect to compounds for use in the treatment of leukodystrophy whereby these compounds are quinoline derivatives, e.g. laquinimod. In a further aspect, the present invention relates to methods for the treatment of Leukodystrophy, in particular, peroxisomal disorders including Zellweger syndrome.