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公开(公告)号:US11278613B2
公开(公告)日:2022-03-22
申请号:US16630951
申请日:2018-07-16
发明人: Kathryn Hashey , Padma Malyala , Marcelo Samsa , Olga Slack , Dong Yu , Alan Stokes , Rashmi Jalah
IPC分类号: A61K39/205 , A61K9/127 , A61K39/00
摘要: Nucleic acid based vaccine constructs encoding Lyssaviral antigens are useful in preventing and treating diseases. Self-amplifying RNA molecules encoding Lyssaviral antigens provide potent and long-lasting immunity.
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公开(公告)号:US20180280301A1
公开(公告)日:2018-10-04
申请号:US15981104
申请日:2018-05-16
发明人: Derek O'Hagan , Manmohan Singh , Siddhartha Jain , Padma Malyala
IPC分类号: A61K9/14 , A61K39/095 , A61J1/00 , A61K39/00
摘要: In one aspect, the present invention provides sterile microparticle compositions comprising biodegradable microparticles, which comprise at least one biodegradable polymer. In other aspects, the present invention provides methods of making and using such compositions as well as articles of manufacture and kits containing the same.
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