-
公开(公告)号：US20220096650A1
公开(公告)日：2022-03-31
申请号：US17426723
申请日：2020-01-31
Inventor： Joanna OPALINSKA
IPC: A61K47/68 , A61K38/07 , A61K39/395 , A61P35/00
Abstract: Disclosed herein are combinations of an antigen binding protein that binds BCMA with an antigen binding protein that bind to an immunomodulatory agent, such as PD-1 or OX40, pharmaceutical compositions thereof, uses thereof, and methods of treatment comprising administering said combinations, including uses in cancer.
-
公开(公告)号：US20230019140A1
公开(公告)日：2023-01-19
申请号：US17846950
申请日：2022-06-22
Inventor： Sanjay KHANDEKAR , Patrick MAYES , Joanna OPALINSKA
IPC: C07K16/28 , A61K47/68 , A61P35/00 , A61K31/573 , A61K31/69 , C07K16/30 , A61K39/395 , C07K19/00
Abstract: Disclosed herein is a method of treating cancer, such as multiple myeloma, involving the combination of an anti-BCMA antigen binding protein (e.g., an anti-BCMA antibody) and a proteasome inhibitor (e.g. bortezomib). The combinations can also include an anti-inflammatory compound (e.g. dexamethasone).
-
公开(公告)号：US20250163172A1
公开(公告)日：2025-05-22
申请号：US19033609
申请日：2025-01-22
Inventor： Sanjay KHANDEKAR , Patrick MAYES , Joanna OPALINSKA
IPC: C07K16/28 , A61K31/573 , A61K31/69 , A61K39/00 , A61K39/395 , A61K47/68 , A61P35/00 , C07K16/30 , C07K19/00
Abstract: Disclosed herein is a method of treating cancer, such as multiple myeloma, involving the combination of an anti-BCMA antigen binding protein (e.g., an anti-BCMA antibody) and a proteasome inhibitor (e.g. bortezomib). The combinations can also include an anti-inflammatory compound (e.g. dexamethasone).
-
公开(公告)号：US20250122297A1
公开(公告)日：2025-04-17
申请号：US18985239
申请日：2024-12-18
Inventor： Sanjay KHANDEKAR , Patrick MAYES , Joanna OPALINSKA
IPC: C07K16/28 , A61K31/454 , A61K31/573 , A61K39/395 , A61K47/68 , A61P35/00
Abstract: Disclosed herein is a method of treating cancer, such as multiple myeloma, involving the combination of an anti-BCMA antigen binding protein (e.g., an anti-BCMA antibody) and an immunomodulatory drug (e.g. pomalidomide or lenalidomide). The combinations can also include an anti-inflammatory compound (e.g. dexamethasone).
-
公开(公告)号：US20220098303A1
公开(公告)日：2022-03-31
申请号：US17426695
申请日：2020-01-31
Inventor： Swethajit Biswas , Nicola A. JACKSON , Elaine Marie PAUL , Herbert STRUEMPER , Joanna OPALINSKA
Abstract: Disclosed herein are combinations of an antigen binding protein that binds BCMA with an antigen binding protein that bind to an immunomodulatory agent, such as PD-1 or OX40, pharmaceutical compositions thereof, uses thereof, and methods of treatment comprising administering said combinations, including uses in cancer.
-
Patent Agency Ranking
公开(公告)号：US20220411512A1
公开(公告)日：2022-12-29
申请号：US17822705
申请日：2022-08-26
Inventor： Axel HOOS , Sanjay KHANDEKAR , Patrick MAYES , Joanna OPALINSKA
Abstract: Disclosed herein is a method of treating cancer, such as multiple myeloma, involving the combination of an anti-BCMA antigen binding protein (e.g., an anti-BCMA antibody) and an immunomodulatory agent (e.g. an agent directed to ICOS or an anti-CD38 antigen binding protein).
-
公开(公告)号：US20200270354A1
公开(公告)日：2020-08-27
申请号：US16646836
申请日：2018-09-12
Inventor： Sanjay KHANDEKAR , Patrick MAYES , Joanna OPALINSKA
IPC: C07K16/28 , A61K31/69 , A61K31/573 , A61K47/68 , A61P35/00
Abstract: Disclosed herein is a method of treating cancer, such as multiple myeloma, involving the combination of an anti-BCMA antigen binding protein (e.g., an anti-BCMA antibody) and a proteasome inhibitor (e.g. bortezomib). The combinations can also include an anti-inflammatory compound (e.g. dexamethasone).
-
公开(公告)号：US20220003772A1
公开(公告)日：2022-01-06
申请号：US17289389
申请日：2019-10-29
Inventor： Elisha J. DETTMAN , Joanna OPALINSKA
IPC: G01N33/574 , A61P35/00 , C07K16/28 , A61K39/395 , A61K45/06
Abstract: This invention relates to methods of treating cancer in a patient need thereof, e.g., in a human subject, comprising determining the level of soluble BCMA (sBCMA) in a sample from the patient, and administering to the patient an effective amount of a BCMA antigen binding protein, thereby treating the cancer in the patient. Also provided are kits for the treatment of cancer comprising a means for determining the level of sBCMA in a sample from a patient.
-
公开(公告)号：US20200255526A1
公开(公告)日：2020-08-13
申请号：US16646921
申请日：2018-09-12
Inventor： Axel HOOS , Sanjay KHANDEKAR , Patrick MAYES , Joanna OPALINSKA
Abstract: Disclosed herein is a method of treating cancer, such as multiple myeloma, involving the combination of an anti-BCMA antigen binding protein (e.g., an anti-BCMA antibody) and an immunomodulatory agent (e.g. an agent directed to ICOS or an anti-CD38 antigen binding protein).
-
公开(公告)号：US20200254093A1
公开(公告)日：2020-08-13
申请号：US16646875
申请日：2018-09-12
Inventor： Sanjay KHANDEKAR , Patrick MAYES , Joanna OPALINSKA
IPC: A61K39/395 , A61K47/68 , A61K31/454 , A61K31/573 , A61P35/00
Abstract: Disclosed herein is a method of treating cancer, such as multiple myeloma, involving the combination of an anti-BCMA antigen binding protein (e.g., an anti-BCMA antibody) and an immunomodulatory drug (e.g. pomalidomide or lenalidomide). The combinations can also include an anti-inflammatory compound (e.g. dexamethasone).
-
-
-
-
-
-
-
-
-
Search Results
10
records
(took 0.016 seconds)
