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公开(公告)号：US20250163172A1
公开(公告)日：2025-05-22
申请号：US19033609
申请日：2025-01-22
Inventor： Sanjay KHANDEKAR , Patrick MAYES , Joanna OPALINSKA
IPC: C07K16/28 , A61K31/573 , A61K31/69 , A61K39/00 , A61K39/395 , A61K47/68 , A61P35/00 , C07K16/30 , C07K19/00
Abstract: Disclosed herein is a method of treating cancer, such as multiple myeloma, involving the combination of an anti-BCMA antigen binding protein (e.g., an anti-BCMA antibody) and a proteasome inhibitor (e.g. bortezomib). The combinations can also include an anti-inflammatory compound (e.g. dexamethasone).
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公开(公告)号：US20250122297A1
公开(公告)日：2025-04-17
申请号：US18985239
申请日：2024-12-18
Inventor： Sanjay KHANDEKAR , Patrick MAYES , Joanna OPALINSKA
IPC: C07K16/28 , A61K31/454 , A61K31/573 , A61K39/395 , A61K47/68 , A61P35/00
Abstract: Disclosed herein is a method of treating cancer, such as multiple myeloma, involving the combination of an anti-BCMA antigen binding protein (e.g., an anti-BCMA antibody) and an immunomodulatory drug (e.g. pomalidomide or lenalidomide). The combinations can also include an anti-inflammatory compound (e.g. dexamethasone).
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公开(公告)号：US20230019140A1
公开(公告)日：2023-01-19
申请号：US17846950
申请日：2022-06-22
Inventor： Sanjay KHANDEKAR , Patrick MAYES , Joanna OPALINSKA
IPC: C07K16/28 , A61K47/68 , A61P35/00 , A61K31/573 , A61K31/69 , C07K16/30 , A61K39/395 , C07K19/00
Abstract: Disclosed herein is a method of treating cancer, such as multiple myeloma, involving the combination of an anti-BCMA antigen binding protein (e.g., an anti-BCMA antibody) and a proteasome inhibitor (e.g. bortezomib). The combinations can also include an anti-inflammatory compound (e.g. dexamethasone).
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公开(公告)号：US20210395367A1
公开(公告)日：2021-12-23
申请号：US17287144
申请日：2019-10-21
Inventor： Elaine Marie PAUL , Patrick MAYES , Catherine E. ELLIS , Jessica KATZ
Abstract: The present invention relates to a method of treating cancer comprising administering to the human an ICOS binding protein or antigen binding portion thereof at a dose of about 0.08 mg to about 240 mg.
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Patent Agency Ranking
公开(公告)号：US20220411512A1
公开(公告)日：2022-12-29
申请号：US17822705
申请日：2022-08-26
Inventor： Axel HOOS , Sanjay KHANDEKAR , Patrick MAYES , Joanna OPALINSKA
Abstract: Disclosed herein is a method of treating cancer, such as multiple myeloma, involving the combination of an anti-BCMA antigen binding protein (e.g., an anti-BCMA antibody) and an immunomodulatory agent (e.g. an agent directed to ICOS or an anti-CD38 antigen binding protein).
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公开(公告)号：US20200270354A1
公开(公告)日：2020-08-27
申请号：US16646836
申请日：2018-09-12
Inventor： Sanjay KHANDEKAR , Patrick MAYES , Joanna OPALINSKA
IPC: C07K16/28 , A61K31/69 , A61K31/573 , A61K47/68 , A61P35/00
Abstract: Disclosed herein is a method of treating cancer, such as multiple myeloma, involving the combination of an anti-BCMA antigen binding protein (e.g., an anti-BCMA antibody) and a proteasome inhibitor (e.g. bortezomib). The combinations can also include an anti-inflammatory compound (e.g. dexamethasone).
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公开(公告)号：US20210324081A1
公开(公告)日：2021-10-21
申请号：US17287358
申请日：2019-10-21
Inventor： Elaine Marie PAUL , Patrick MAYES , Catherine E. ELLIS , Jessica KATZ
IPC: C07K16/28 , A61K9/00 , A61P35/00 , A61K39/395
Abstract: The present invention relates to a method of treating cancer comprising administering to the human an ICOS binding protein or antigen binding portion thereof at a dose of about 0.08 mg to about 240 mg and administering to the human a PD1 antagonist.
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公开(公告)号：US20200255526A1
公开(公告)日：2020-08-13
申请号：US16646921
申请日：2018-09-12
Inventor： Axel HOOS , Sanjay KHANDEKAR , Patrick MAYES , Joanna OPALINSKA
Abstract: Disclosed herein is a method of treating cancer, such as multiple myeloma, involving the combination of an anti-BCMA antigen binding protein (e.g., an anti-BCMA antibody) and an immunomodulatory agent (e.g. an agent directed to ICOS or an anti-CD38 antigen binding protein).
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公开(公告)号：US20200254093A1
公开(公告)日：2020-08-13
申请号：US16646875
申请日：2018-09-12
Inventor： Sanjay KHANDEKAR , Patrick MAYES , Joanna OPALINSKA
IPC: A61K39/395 , A61K47/68 , A61K31/454 , A61K31/573 , A61P35/00
Abstract: Disclosed herein is a method of treating cancer, such as multiple myeloma, involving the combination of an anti-BCMA antigen binding protein (e.g., an anti-BCMA antibody) and an immunomodulatory drug (e.g. pomalidomide or lenalidomide). The combinations can also include an anti-inflammatory compound (e.g. dexamethasone).
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