公开(公告)号：US20170152251A1

公开(公告)日：2017-06-01

申请号：US15325521

申请日：2014-07-18

Applicant: GREEN CROSS CORPORATION ,  LEGOCHEM BIOSCIENCES,INC.

Inventor： Soongyu CHOI ,  Jungsub CHOI ,  So-Hyun YOON ,  Yoo Hoon KIM ,  Jae Yeon KIM ,  Suk Ho LEE ,  Young Lag CHO ,  Ho Young SONG ,  Dae Yon LEE ,  Sung Yoon BAEK ,  Sang Eun CHAE ,  Tae Kyo PARK ,  Sung Ho WOO ,  Yong Zu KIM

IPC: C07D413/14

CPC classification number: C07D413/14 ,  A61K31/53 ,  A61P7/02 ,  A61P9/00 ,  A61P29/00 ,  C07B2200/13 ,  C07D253/065 ,  C07D409/10

Abstract: The present invention relates to a novel crystalline form of 5-chloro-N-({(5S)-2-oxo-3-[4-(5,6-dihydro-4H-[1,2,4]triazin-1-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide methanesulfonate and a pharmaceutical composition containing the same. The novel crystalline form of a compound according to the present invention exhibits excellent stability even in high-temperature and humidity environments, and thus can be favorably used to prevent or treat diseases, such as thrombosis, myocardial infarction, atherosclerosis, inflammation, stroke, angina pectoris, restenosis after angioplasty, and thromboembolism.