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公开(公告)号:US20080044465A1
公开(公告)日:2008-02-21
申请号:US11846351
申请日:2007-08-28
申请人: Gary Firestein , Nathan Zvaifler , Douglas Green
发明人: Gary Firestein , Nathan Zvaifler , Douglas Green
IPC分类号: A61K31/711 , A61K9/00 , A61K9/127 , A61P1/00 , A61P19/02
CPC分类号: A61K31/711 , A61K38/1758 , A61K38/1761 , A61K48/00 , A61K48/005
摘要: The present invention provides a novel method for the treatment of cellular accumulation in chronic inflammatory diseases such as rheumatoid arthritis. The method includes gene delivery and gene expression that is capable of enhancing apoptosis of accumulating cells and those cells which recruit accumulating cells. Also provided are diagnostic methods for detecting cellular accumulation diseases.
摘要翻译: 本发明提供了一种治疗慢性炎性疾病如类风湿性关节炎中细胞积累的新方法。 该方法包括能够增强蓄积细胞凋亡的基因递送和基因表达以及募集累积细胞的那些细胞。 还提供了用于检测细胞积聚疾病的诊断方法。