公开(公告)号：US6066149A

公开(公告)日：2000-05-23

申请号：US941514

申请日：1997-09-30

申请人： Gene Samson ,  Harold F. Carrison

发明人： Gene Samson ,  Harold F. Carrison

IPC分类号： A61B17/22 ,  A61B19/00 ,  A61F2/01

CPC分类号： A61F2/013 ,  A61B17/221 ,  A61F2/01 ,  A61B2017/22034 ,  A61B2017/22045 ,  A61B2017/22084 ,  A61B2017/2212 ,  A61B2090/376 ,  A61B90/39 ,  A61F2002/011 ,  A61F2002/016 ,  A61F2230/0006 ,  A61F2230/005 ,  A61F2230/0067 ,  A61F2230/0071

摘要： This is a surgical device usually delivered through an intravascular catheter. It may be used in several ways. It may, for instance, be used to open a clear passageway adjacent thrombus to allow both blood and medication to bypass the clot. It may be used to pierce and to remove thrombus. These thrombus are often found in tortuous vasculature. The device includes several sections. The device has a core element, typically a core wire. Placed around the distal end of the core element is a collapsible but preferably self expanding proximal cage assembly and a distal filter, preferably a self-expanding cage assembly or other filter component. The various portions of those components are preferably radio-opaque. The proximal end of the proximal cage is typically is affixed to an actuator in such a way as to allow expansion of the cage after deployment. The proximal cage assembly may be used for collecting emboli or for displacing them to allow blood flow to resume, either with or without concurrent clot-dissolving drug treatment. The distal sector, whether a self-expanding cage or fan, is placed distally of the thrombus to collect portions of the thrombus which may loosen during the treatment or removal procedure.

公开(公告)号：US20110082493A1

公开(公告)日：2011-04-07

申请号：US12966311

申请日：2010-12-13

申请人： Gene Samson ,  Harold F. Carrison

发明人： Gene Samson ,  Harold F. Carrison

IPC分类号： A61F2/01

CPC分类号： A61F2/013 ,  A61B17/221 ,  A61B90/39 ,  A61B2017/22034 ,  A61B2017/22045 ,  A61B2017/22084 ,  A61B2017/2212 ,  A61B2090/376 ,  A61F2/01 ,  A61F2002/011 ,  A61F2002/016 ,  A61F2230/0006 ,  A61F2230/005 ,  A61F2230/0067 ,  A61F2230/0071

摘要： This is a surgical device usually delivered through an intravascular catheter. It may be used in several ways. It may, for instance, be used to open a clear passageway adjacent thrombus to allow both blood and medication to bypass the clot. It may be used to pierce and to remove thrombus. These thrombus are often found in tortuous vasculature. The device includes several sections. The device has a core element, typically a core wire. Placed around the distal end of the core element is a collapsible but preferably self expanding proximal cage assembly and a distal filter, preferably a self-expanding cage assembly or other filter component. The various portions of those components are preferably radio-opaque. The proximal end of the proximal cage is typically is affixed to an actuator in such a way as to allow expansion of the cage after deployment. The proximal cage assembly may be used for collecting emboli or for displacing them to allow blood flow to resume, either with or without concurrent clot-dissolving drug treatment. The distal sector, whether a self-expanding cage or fan, is placed distally of the thrombus to collect portions of the thrombus which may loosen during the treatment or removal procedure.

摘要翻译： 这是通常通过血管内导管递送的手术装置。 它可以以几种方式使用。 例如，它可以用于打开邻近血栓的清晰通道，以允许血液和药物绕过凝块。 它可以用于刺穿和去除血栓。 这些血栓通常在曲折的脉管系统中发现。 该设备包括几个部分。 该装置具有核心元件，通常为芯线。 围绕芯元件的远端放置的是可折叠但优选自扩张的近端保持器组件和远端过滤器，优选自膨胀笼组件或其它过滤器部件。 这些部件的各个部分优选地是不透射线的。 近端保持架的近端通常被固定到致动器上，以允许在展开之后使笼膨胀。 近端笼组件可用于收集栓塞或用于置换它们以允许血流恢复，无论是否伴有凝血溶解药物治疗。 远端部分，无论是自膨胀笼或风扇，是否位于血栓的远端，以收集在治疗或移除手术过程中可能松动的部分血栓。

公开(公告)号：US07875050B2

公开(公告)日：2011-01-25

申请号：US10082492

申请日：2002-02-22

申请人： Gene Samson ,  Harold F Carrison

发明人： Gene Samson ,  Harold F Carrison

IPC分类号： A61M29/00

CPC分类号： A61F2/013 ,  A61B17/221 ,  A61B90/39 ,  A61B2017/22034 ,  A61B2017/22045 ,  A61B2017/22084 ,  A61B2017/2212 ,  A61B2090/376 ,  A61F2/01 ,  A61F2002/011 ,  A61F2002/016 ,  A61F2230/0006 ,  A61F2230/005 ,  A61F2230/0067 ,  A61F2230/0071

摘要： An embolism treatment device includes an elongated core wire having a coil tip coupled to the distal end of the core wire and a cage assembly substantially coaxial to the core wire, having a first deployment shape and a second expanded shape. The core wire is freely moveable axially through the cage assembly. The device additionally includes an inner coil surrounding the core wire within the cage assembly and an actuator element, having a first position and a second position, located proximally to the cage assembly, wherein when the actuator element is in the first position, the cage assembly is in the first deployment shape and when the actuator element is in the second position, the cage assembly is in the second expanded shape.

摘要翻译： 栓塞治疗装置包括细长的芯线，其具有联接到芯线的远端的线圈末端和与芯线基本同轴的保持架组件，具有第一展开形状和第二扩张形状。 芯线可以轴向自由移动通过保持架组件。 该装置还包括围绕保持架组件内的芯线的内部线圈和具有位于保持架组件的近侧的第一位置和第二位置的致动器元件，其中当致动器元件处于第一位置时，保持架组件 处于第一展开形状，并且当致动器元件处于第二位置时，保持架组件处于第二展开形状。

公开(公告)号：US06383205B1

公开(公告)日：2002-05-07

申请号：US09452528

申请日：1999-12-01

申请人： Gene Samson ,  Harold F. Carrison

发明人： Gene Samson ,  Harold F. Carrison

IPC分类号： A61M2900

CPC分类号： A61F2/013 ,  A61B17/221 ,  A61B90/39 ,  A61B2017/22034 ,  A61B2017/22045 ,  A61B2017/22084 ,  A61B2017/2212 ,  A61B2090/376 ,  A61F2/01 ,  A61F2002/011 ,  A61F2002/016 ,  A61F2230/0006 ,  A61F2230/005 ,  A61F2230/0067 ,  A61F2230/0071

摘要： A surgical device for opening a passageway adjacent a thrombus to allow both blood and medication to bypass a clot. The surgical device may also be used to pierce and remove a thrombus. The device includes a core element or wire having an expanding proximal cage assembly and a distal filter or expanding cage assembly placed around the core wire. Components of the device are preferably radio-opaque. The proximal end of the proximal cage may be affixed to an actuator to allow expansion of the cage after deployment. The proximal cage assembly may be used for collecting emboli or for displacing emboli to allow blood flow to resume, either with or without concurrent clot-dissolving drug treatment. The distal section is placed distally of the thrombus to collect portions of the thrombus which may loosen during the treatment or removal procedure.

摘要翻译： 用于打开邻近血栓的通道以允许血液和药物绕过凝块的手术装置。 手术装置也可以用于刺穿和去除血栓。 该装置包括具有扩展的近侧保持架组件和放置在芯线周围的远端过滤器或扩展笼组件的芯元件或线。 该装置的组件优选地是不透射线的。 近端保持架的近端可以固定到致动器以允许在展开之后使笼延伸。 近端笼组件可用于收集栓塞或用于置换栓塞以允许血流恢复，无论是否伴有凝血溶解药物治疗。 远侧部分放置在血栓的远端，以收集在治疗或移除手术过程中可能松动的血栓部分。

公开(公告)号：US08486104B2

公开(公告)日：2013-07-16

申请号：US12966311

申请日：2010-12-13

申请人： Gene Samson ,  Harold F. Carrison

发明人： Gene Samson ,  Harold F. Carrison

IPC分类号： A61M29/00

CPC分类号： A61F2/013 ,  A61B17/221 ,  A61B90/39 ,  A61B2017/22034 ,  A61B2017/22045 ,  A61B2017/22084 ,  A61B2017/2212 ,  A61B2090/376 ,  A61F2/01 ,  A61F2002/011 ,  A61F2002/016 ,  A61F2230/0006 ,  A61F2230/005 ,  A61F2230/0067 ,  A61F2230/0071

摘要： This is a surgical device usually delivered through an intravascular catheter. It may be used in several ways. It may, for instance, be used to open a clear passageway adjacent thrombus to allow both blood and medication to bypass the clot. It may be used to pierce and to remove thrombus. These thrombus are often found in tortuous vasculature. The device includes several sections. The device has a core element, typically a core wire. Placed around the distal end of the core element is a collapsible but preferably self expanding proximal cage assembly and a distal filter, preferably a self-expanding cage assembly or other filter component. The various portions of those components are preferably radio-opaque. The proximal end of the proximal cage is typically is affixed to an actuator in such a way as to allow expansion of the cage after deployment. The proximal cage assembly may be used for collecting emboli or for displacing them to allow blood flow to resume, either with or without concurrent clot-dissolving drug treatment. The distal sector, whether a self-expanding cage or fan, is placed distally of the thrombus to collect portions of the thrombus which may loosen during the treatment or removal procedure.

公开(公告)号：US06197014B1

公开(公告)日：2001-03-06

申请号：US09038654

申请日：1998-03-11

申请人： Gene Samson ,  Hanh Doan

发明人： Gene Samson ,  Hanh Doan

IPC分类号： A61M2500

CPC分类号： A61M25/005 ,  A61M25/0053 ,  A61M25/007 ,  A61M2025/0079

摘要： This is a catheter section having a number of radially placed holes through the catheter section wall and a catheter assembly including that section. That catheter assembly may be used in accessing and treating a tissue target within the body, typically one which is accessible through the vascular system. Central to the catheter section is the presence of a braided metallic reinforcing member, typically of super-elastic alloy ribbon, situated in such a way to provide an exceptionally thin wall, controlled stiffness, high resistance to kinking, and complete recovery in vivo from kinking situations. The orifices in the section are optimally placed in the interstices between the turns of the braid. The braid may have a single pitch or may vary in pitch along the axis of the catheter or catheter section. The braided ribbon reinforcing member typically is placed between a flexible outer tubing member and an inner tubing member to produce a catheter section which is very flexible but highly kink resistant. The catheter sections made according to this invention may be used alone or in conjunction with other catheter sections either made using the concepts shown herein or made in other ways. The more proximal sections of the catheter assembly are often substantially stiffer than the more distal sections due to the presence of stiff polymeric tubing or metallic tubing or composited materials in the stiffer section.

摘要翻译： 这是具有穿过导管部分壁的多个径向放置的孔的导管部分和包括该部分的导管组件。 该导管组件可用于进入和治疗身体内的组织靶，通常是可通过血管系统接近的组织靶。 导管部分的中心是存在通常为超弹性合金带的编织金属加强构件，其以这样的方式设置，以提供非常薄的壁，受控刚度，高抗扭结和体内从扭结中完全恢复 情况 该部分的孔口最佳地放置在编织物匝间的间隙中。 编织物可以具有单个间距，或者可以沿着导管或导管部分的轴线变化。 编织带加强构件通常放置在柔性外管构件和内管构件之间以产生非常柔性但高度扭结的导管段。根据本发明制造的导管段可以单独使用或与其他结合使用 导管部分使用本文所示的概念或以其他方式制造。 由于在刚性部分中存在刚性聚合物管或金属管或合成材料，所以导管组件的近端部分通常比较远的部分更坚硬。

公开(公告)号：US6143013A

公开(公告)日：2000-11-07

申请号：US641259

申请日：1996-04-30

申请人： Gene Samson ,  Uriel Hiram Chee ,  Kim Nguyen ,  Edward J. Snyder ,  Erik T. Engelson

发明人： Gene Samson ,  Uriel Hiram Chee ,  Kim Nguyen ,  Edward J. Snyder ,  Erik T. Engelson

IPC分类号： A61M25/00 ,  A61M25/16 ,  A61M29/00

CPC分类号： A61M25/005 ,  A61M2025/0081 ,  A61M25/0053 ,  A61M25/0054

摘要： This is a catheter assembly and a section of that catheter assembly. That catheter assembly may be used in accessing a tissue target within the body, typically a target which is accessible through the vascular system. Central to the invention is the use of a braided metallic reinforcing member, typically of super-elastic alloy ribbon, situated within the catheter body in such a way to create a catheter having an exceptionally thin wall, controlled stiffness, high resistance to kinking, and complete recovery in vivo from kinking situations. The braid may have a single pitch or may vary in pitch along the axis of the catheter or catheter section. The braided ribbon reinforcing member typically is placed between a flexible outer tubing member and an inner tubing member to produce a catheter section which is very flexible but highly kink resistant. The catheter sections made according to this invention may be used alone or in conjunction with other catheter sections either made using the concepts shown herein or made in other ways. The more proximal sections of the catheter assembly are often substantially stiffer than the more distal sections due to the presence of stiff polymeric tubing or metallic tubing or composited materials in the stiffer section.

摘要翻译： 这是导管组件和导管组件的一部分。 该导管组件可用于进入体内的组织靶，通常是通过血管系统可接近的靶。 本发明的中心是使用位于导管主体内的编织金属加强构件，通常为超弹性合金带，以形成具有特别薄壁，受控刚度，高抗扭结性的导管，以及 从扭结情况完全恢复体内。 编织物可以具有单个间距，或者可以沿着导管或导管部分的轴线变化。 编织带加强构件通常放置在柔性外管构件和内管构件之间以产生非常柔性但高度扭结的导管部分。 根据本发明制造的导管部分可以单独使用或与使用本文所示的概念或以其他方式制成的其它导管部分结合使用。 由于在刚性部分中存在刚性聚合物管或金属管或合成材料，所以导管组件的近端部分通常比较远的部分更坚硬。

公开(公告)号：US6143007A

公开(公告)日：2000-11-07

申请号：US431360

申请日：1995-04-28

申请人： Michael J. Mariant ,  Gene Samson

发明人： Michael J. Mariant ,  Gene Samson

IPC分类号： A61F2/84 ,  A61B17/12 ,  A61B17/00

CPC分类号： A61B17/12022 ,  A61B17/1215

摘要： This invention is a surgical device. In particular, it is an implant which may be used to occlude vascular lumens, arteries, veins, aneurysms, vascular malformations, arteriovenous fistulas, or other cavities and lumens within a mammalian body. It is typically a substrate coil or braid to which a number of fibers have been secured using heat.

摘要翻译： 本发明是一种手术装置。 特别地，它是可以用于阻塞哺乳动物体内的血管腔，动脉，静脉，动脉瘤，血管畸形，动静脉瘘或其它腔和腔的植入物。 通常是使用热量固定多根纤维的基底线圈或编织物。

公开(公告)号：US5906606A

公开(公告)日：1999-05-25

申请号：US607847

申请日：1996-02-27

申请人： Uriel Hiram Chee ,  Erik T. Engelson ,  Gene Samson

发明人： Uriel Hiram Chee ,  Erik T. Engelson ,  Gene Samson

IPC分类号： A61F2/958 ,  A61M25/00

CPC分类号： A61M25/1027 ,  A61M25/005 ,  A61M25/10 ,  A61M2025/0079 ,  A61M2025/09183 ,  A61M25/0053 ,  A61M25/0054

摘要： This is a balloon catheter having braided layer which extends generally from the proximal end of the catheter to a location distal of the balloon. In particular, it is desirable that the shaft of the catheter proximal of the balloon be stiffest at the proximal section and least stiff just proximal of the balloon. Although the catheter may be a single lumen catheter using some type of a core wire to act as a valve for inflation and deflation of the balloon, it is within the scope of the invention to include either a separate inflation/deflation lumen or one incorporated into the various concentric polymeric layers used to make up the proximal shaft. Particularly preferred is the use of an elastic, compliant balloon.

摘要翻译： 这是具有编织层的球囊导管，其通常从导管的近端延伸到气囊的远侧的位置。 特别地，期望球囊近端的导管的轴在近端部分处是最刚性的，并且最接近刚好在气囊附近。 尽管导管可以是使用某种类型的芯线作为气囊充气和放气的阀的单腔导管，但是在本发明的范围内还包括单独的充气/放气管腔或并入 用于构成近端轴的各种同心聚合物层。 特别优选的是使用弹性的柔顺气球。

公开(公告)号：US5853400A

公开(公告)日：1998-12-29

申请号：US868036

申请日：1997-06-03

申请人： Gene Samson

发明人： Gene Samson

IPC分类号： F16L11/12 ,  A61M25/00 ,  A61M25/16

CPC分类号： A61M25/0053 ,  A61M25/005

摘要： This invention is a surgical device. In particular, it is a catheter suitable for accessing a tissue target within the body, typically a target which is accessible through the vascular system. Central to the invention is the use of a stiffener ribbon, typically metallic, wound within the catheter body in such a way as to create a catheter having a controllable stiffness. The stiffener ribbon is adhesively bonded to a flexible outer tubing member so to produce a thin wall catheter section which is exceptionally flexible but highly kink resistant. The catheter sections made according to this invention may be used in conjunction with other catheter sections either using the concepts shown herein or made in other ways. Because of the effective strength and ability to retain a generally kink-free form, these catheters may be effectively used in sizes which are quite fine, e.g., 0.015" to 0.020" in diameter, and useable within typical vascular catheters.

摘要翻译： 本发明是一种手术装置。 特别地，它是适于进入体内的组织靶的导管，通常是可通过血管系统接近的靶。 本发明的中心是使用加强筋（通常是金属的）缠绕在导管体内，以便产生具有可控刚度的导管。 加强筋粘合到柔性外管构件上，以便产生非常灵活但高度扭结的薄壁导管段。 根据本发明制造的导管部分可以使用本文所示的概念或以其他方式制造的其他导管部分结合使用。 由于有效的强度和保持一般无扭结形式的能力，这些导管可以有效地用于相当细的尺寸，例如直径为0.015“至0.020”，并且可用于典型的血管导管。