公开(公告)号：US20230357418A1

公开(公告)日：2023-11-09

申请号：US18245372

申请日：2021-03-19

Applicant: Genentech, Inc.

Inventor： Shalini V. MOHAN ,  William George REISS ,  Hoi Ying Linda YAU ,  Benjamin Howard KRAMER ,  Jian HAN

IPC: C07K16/28 ,  A61K31/706 ,  A61K31/573 ,  A61P11/00

CPC classification number: C07K16/2866 ,  A61K31/706 ,  A61K31/573 ,  A61P11/00 ,  A61K2039/545

Abstract: The application disclosed concerns a method of treating pneumonia in a patient who is not mechanically ventilated comprising administering an IL-6 antagonist (e.g. tocilizumab) to the patient in an amount effective to prevent the patient from dying or receiving mechanical ventilation. The disclosure is based on the results of the EM PACTA clinical trial.