公开(公告)号：US20220081466A1

公开(公告)日：2022-03-17

申请号：US17332907

申请日：2021-05-27

Applicant: Genentech, Inc.

Inventor： Arick BROWN ,  Christopher J. DOWD ,  Asha Nandini-Radhamohan KEBA

IPC: C07K1/22

Abstract: The present invention provides methods for purifying a polypeptide comprising a CH2/CH3 region, comprising binding the polypeptide to Protein A and eluting with a pH gradient starting at a low pH.

公开(公告)号：US20220324905A1

公开(公告)日：2022-10-13

申请号：US17558406

申请日：2021-12-21

Applicant: Genentech, Inc.

Inventor： Arick BROWN ,  Christopher J. DOWD ,  Asha Nandini-Radhamohan KEBA

IPC: C07K1/22

Abstract: The present invention provides methods for purifying a polypeptide comprising a CH2/CH3 region, comprising binding the polypeptide to Protein A and eluting with a pH gradient starting at a low pH.