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公开(公告)号：US20240369575A1
公开(公告)日：2024-11-07
申请号：US18587851
申请日：2024-02-26
Applicant: Genentech, Inc.
Inventor： Marissa Lynn MATSUMOTO , Domagoj VUCIC , Tatiana GONCHAROV
Abstract: Multispecific antibodies comprising a first half antibody comprising a first antigen binding site that binds to a polyubiquitin; and a second half antibody comprising a second antigen binding site that binds a pro-inflammatory protein, such as receptor-interacting protein kinase 1 (RIP1) or receptor-interacting protein kinase 2 (RIP2), as well as methods for using the antibodies, are provided.
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