公开(公告)号：US20240150491A1

公开(公告)日：2024-05-09

申请号：US18389748

申请日：2023-12-19

Applicant: Genentech, Inc.

Inventor： James Thomas KOERBER ,  Wyne Pun LEE ,  Tangsheng YI ,  Juan ZHANG ,  Cary Dean AUSTIN ,  Cecilia P.C. CHIU ,  Joseph Edward CHAVARRIA-SMITH ,  Jawahar SUDHAMSU

IPC: C07K16/40 ,  A61K39/395 ,  A61P17/00

CPC classification number: C07K16/40 ,  A61K39/3955 ,  A61P17/00 ,  A61K2039/507

Abstract: The invention provides anti-KLK7 antibodies, anti-KLK5 antibodies, anti-KLK5/KLK7 multispecific antibodies, and methods of using the same.

公开(公告)号：US20140134638A1

公开(公告)日：2014-05-15

申请号：US14077407

申请日：2013-11-12

Applicant: Genentech, Inc.

Inventor： Juan ZHANG ,  Mercedesz BALAZS ,  Ning CHAI ,  Henry CHIU ,  Wyne Pun LEE ,  Zhonghua LIN ,  Patrick LUPARDUS ,  Lee SWEM

IPC: C12N5/0789

CPC classification number: C07K16/1018 ,  C07K16/00 ,  C07K16/065 ,  C07K16/1282 ,  C07K2317/30 ,  C12N5/0635

Abstract: The present invention relates to methods for enrichment of antigen-specific plasmablasts. The methods are useful for the identification of antibodies, including rare antibodies which recognize more than one antigen.

Abstract translation: 本发明涉及用于富集抗原特异性浆细胞的方法。 该方法可用于鉴定抗体，包括识别多于一种抗原的罕见抗体。