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公开(公告)号:US20220153842A1
公开(公告)日:2022-05-19
申请号:US17516979
申请日:2021-11-02
Applicant: Genentech, Inc.
Inventor: Chi-Chung LI , Carol Elaine O'HEAR , Stephen James SIMKO, III , Iris Tranthuyngan TO , Klara TOTPAL , Hong WANG , Michael C. WEI , Shen YIN , Brendan Christian BENDER , Xi CHEN , Yu-Waye CHU , Maria HRISTOPOULOS
Abstract: The present invention relates to the treatment of subjects having CD20-positive cell proliferative disorders (e.g., B cell proliferative disorders, such as non-Hodgkin's lymphomas). More specifically, the invention pertains to the treatment of subjects having a CD20-positive cell proliferative disorder (e.g., B cell proliferative disorder) by administering a combination of an anti-CD20/anti-CD3 bispecific antibody and an anti-CD79b antibody drug conjugate.
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公开(公告)号:US20180134798A1
公开(公告)日:2018-05-17
申请号:US15813657
申请日:2017-11-15
Applicant: Genentech, Inc.
Inventor: Yu-Waye CHU , Iraj HOSSEINI , Saroja RAMANUJAN , Kapil GADKAR , Chi-Chung LI
IPC: C07K16/28 , A61K31/573 , A61K39/395
CPC classification number: C07K16/2887 , A61K31/573 , A61K39/3955 , A61K2039/507 , A61K2039/54 , A61K2039/545 , C07K16/2809 , C07K16/2827 , C07K16/2866 , C07K2317/24 , C07K2317/31 , C07K2317/41
Abstract: The invention provides methods of dosing for the treatment of cancers, such as B cell proliferative disorders, with anti-cluster of differentiation 20 (CD20)/anti-cluster of differentiation 3 (CD3) bispecific antibodies.
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公开(公告)号:US20250073212A1
公开(公告)日:2025-03-06
申请号:US18661293
申请日:2024-05-10
Applicant: Genentech, Inc.
Inventor: Andrew POLSON , Shang-Fan YU , Yu-Waye CHU , Michael WENGER , Jamie Harue HIRATA , Dan LU
IPC: A61K31/4184 , A61K31/454 , A61K31/553 , A61K31/635 , A61K39/00 , A61K39/395 , A61K45/06 , A61K47/68 , C07K16/28 , C07K16/30
Abstract: Provided herein are methods of treating B-cell proliferative disorders in particular Follicular Lymphoma and/or Diffuse Large B-Cell Lymphoma using immunoconjugates comprising anti-CD79b antibodies in combination with additional therapeutic agents.
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公开(公告)号:US20240132613A1
公开(公告)日:2024-04-25
申请号:US18531287
申请日:2023-12-06
Applicant: Genentech, Inc.
Inventor: Yu-Waye CHU , Iraj HOSSEINI , Saroja RAMANUJAN , Kapil GADKAR , Chi-Chung LI
IPC: C07K16/28 , A61K31/573 , A61K39/395
CPC classification number: C07K16/2887 , A61K31/573 , A61K39/3955 , C07K16/2809 , C07K16/2827 , C07K16/2866 , A61K2039/507
Abstract: The invention provides methods of dosing for the treatment of cancers, such as B cell proliferative disorders, with anti-cluster of differentiation 20 (CD20)/anti-cluster of differentiation 3 (CD3) bispecific antibodies.
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公开(公告)号:US20210346352A1
公开(公告)日:2021-11-11
申请号:US17316592
申请日:2021-05-10
Applicant: Genentech, Inc.
Inventor: Andrew POLSON , Shang-Fan YU , Yu-Waye CHU , Michael WENGER , Jamie Harue HIRATA , Dan LU
IPC: A61K31/4184 , A61K39/395 , A61K47/68 , A61K45/06 , C07K16/28 , C07K16/30 , A61K31/553 , A61K31/454 , A61K31/635
Abstract: Provided herein are methods of treating B-cell proliferative disorders in particular Follicular Lymphoma and/or Diffuse Large B-Cell Lymphoma using immunoconjugates comprising anti-CD79b antibodies in combination with additional therapeutic agents.
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公开(公告)号:US20190201382A1
公开(公告)日:2019-07-04
申请号:US16358410
申请日:2019-03-19
Applicant: Genentech, Inc.
Inventor: Andrew POLSON , Shang-Fan YU , Yu-Waye CHU , Michael WENGER
IPC: A61K31/4184 , A61K39/395 , A61K45/06 , C07K16/28 , A61K47/68 , C07K16/30
CPC classification number: A61K31/4184 , A61K31/454 , A61K31/553 , A61K31/635 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K47/6867 , A61K47/6889 , A61K2039/507 , A61K2039/54 , A61K2039/545 , A61K2300/00 , C07K16/2803 , C07K16/2887 , C07K16/3061 , C07K2317/24
Abstract: Provided herein are methods of treating B-cell proliferative disorders in particular Follicular Lymphoma and/or Diffuse Large B-Cell Lymphoma using immunoconjugates comprising anti-CD79b antibodies in combination with additional therapeutic agents.
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