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公开(公告)号：US20210346352A1
公开(公告)日：2021-11-11
申请号：US17316592
申请日：2021-05-10
申请人： Genentech, Inc.
发明人： Andrew POLSON , Shang-Fan YU , Yu-Waye CHU , Michael WENGER , Jamie Harue HIRATA , Dan LU
IPC分类号： A61K31/4184 , A61K39/395 , A61K47/68 , A61K45/06 , C07K16/28 , C07K16/30 , A61K31/553 , A61K31/454 , A61K31/635
摘要： Provided herein are methods of treating B-cell proliferative disorders in particular Follicular Lymphoma and/or Diffuse Large B-Cell Lymphoma using immunoconjugates comprising anti-CD79b antibodies in combination with additional therapeutic agents.
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公开(公告)号：US20170239366A1
公开(公告)日：2017-08-24
申请号：US15386577
申请日：2016-12-21
申请人： Genentech, Inc.
发明人： Steven R. LEONG , Andrew POLSON , Paul POLAKIS , Yan WU , Wei-Ching LIANG , Ron FIRESTEIN
IPC分类号： A61K47/48 , A61K31/5377 , C07K16/30 , A61K31/5517 , A61K39/395 , C07K19/00
CPC分类号： C07K16/3015 , A61K31/5377 , A61K31/5517 , A61K39/3955 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K51/1027 , A61K2039/505 , C07K16/2827 , C07K16/3069 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/41 , C07K2317/567 , C07K2317/77 , C07K2317/92 , G01N33/57492 , A61K2300/00
摘要： The invention provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号：US20200247887A1
公开(公告)日：2020-08-06
申请号：US16600331
申请日：2019-10-11
申请人： Genentech, Inc.
发明人： Yvonne CHEN , Mark DENNIS , David DORNAN , Kristi ELKINS , Jagath Reddy JUNUTULA , Andrew POLSON , Bing ZHENG
IPC分类号： C07K16/28 , G01N33/574 , C07K16/30 , A61K38/05 , A61K31/537 , A61K45/06 , A61K39/395 , A61K47/68 , A61K51/10
摘要： The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号：US20200079852A1
公开(公告)日：2020-03-12
申请号：US16691437
申请日：2019-11-21
申请人： Genentech, Inc.
发明人： Yvonne CHEN , Mark DENNIS , David DORNAN , Kristi ELKINS , Jagath Reddy JUNUTULA , Andrew POLSON , Bing ZHENG
IPC分类号： C07K16/28 , A61K45/06 , A61K39/395 , G01N33/574 , A61K47/68 , A61K51/10 , C07K16/30 , A61K31/537 , A61K38/05
摘要： The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号：US20190201382A1
公开(公告)日：2019-07-04
申请号：US16358410
申请日：2019-03-19
申请人： Genentech, Inc.
发明人： Andrew POLSON , Shang-Fan YU , Yu-Waye CHU , Michael WENGER
IPC分类号： A61K31/4184 , A61K39/395 , A61K45/06 , C07K16/28 , A61K47/68 , C07K16/30
CPC分类号： A61K31/4184 , A61K31/454 , A61K31/553 , A61K31/635 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K47/6867 , A61K47/6889 , A61K2039/507 , A61K2039/54 , A61K2039/545 , A61K2300/00 , C07K16/2803 , C07K16/2887 , C07K16/3061 , C07K2317/24
摘要： Provided herein are methods of treating B-cell proliferative disorders in particular Follicular Lymphoma and/or Diffuse Large B-Cell Lymphoma using immunoconjugates comprising anti-CD79b antibodies in combination with additional therapeutic agents.
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公开(公告)号：US20170058032A1
公开(公告)日：2017-03-02
申请号：US15349964
申请日：2016-11-11
申请人： Genentech, Inc.
发明人： Yvonne CHEN , Mark DENNIS , David DORNAN , Kristi ELKINS , Jagath Reddy JUNUTULA , Andrew POLSON , Bing ZHENG
IPC分类号： C07K16/28 , A61K45/06 , A61K39/395 , A61K47/48
摘要： The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
摘要翻译： 本发明涉及可用于治疗哺乳动物造血肿瘤的物质组合物，以及使用这些物质组合物的方法。
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公开(公告)号：US20240309088A1
公开(公告)日：2024-09-19
申请号：US18392623
申请日：2023-12-21
申请人： Genentech, Inc.
发明人： Yvonne CHEN , Mark DENNIS , David DORNAN , Kristi ELKINS , Jagath Reddy JUNUTULA , Andrew POLSON , Bing ZHENG
IPC分类号： C07K16/28 , A61K31/537 , A61K38/05 , A61K39/00 , A61K39/395 , A61K45/06 , A61K47/68 , A61K51/10 , C07K16/30 , G01N33/574
CPC分类号： C07K16/2803 , A61K31/537 , A61K38/05 , A61K39/39558 , A61K45/06 , A61K47/6803 , A61K47/6811 , A61K47/6849 , A61K47/6867 , A61K51/1027 , C07K16/3061 , G01N33/57492 , A61K2039/505 , C07K2317/24 , C07K2317/34 , C07K2317/40 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/92 , Y02A50/30
摘要： The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号：US20220251197A1
公开(公告)日：2022-08-11
申请号：US17725417
申请日：2022-04-20
申请人： Genentech, Inc.
发明人： Yvonne CHEN , Mark DENNIS , David DORNAN , Kristi ELKINS , Jagat Reddy JUNUTULA , Andrew POLSON , Bing ZHENG
IPC分类号： C07K16/28 , A61K51/10 , A61K47/68 , A61K39/395 , A61K45/06 , A61K31/537 , A61K38/05 , C07K16/30 , G01N33/574
摘要： The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号：US20220023437A1
公开(公告)日：2022-01-27
申请号：US17234695
申请日：2021-04-19
申请人： Genentech, Inc.
发明人： Yvonne CHEN , Mark DENNIS , Kristi ELKINS , Jagath Reddy JUNUTULA , Andrew POLSON , Bing ZHENG
摘要： The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号：US20150314016A1
公开(公告)日：2015-11-05
申请号：US14734957
申请日：2015-06-09
申请人： Genentech, Inc.
发明人： Yvonne CHEN , Mark DENNIS , David DORNAN , Kristi ELKINS , Jagath Reddy JUNUTULA , Andrew POLSON , Bing ZHENG
IPC分类号： A61K47/48 , A61K38/05 , A61K31/537 , A61K51/10
CPC分类号： C07K16/2803 , A61K31/537 , A61K38/05 , A61K39/39558 , A61K45/06 , A61K47/6803 , A61K47/6811 , A61K47/6849 , A61K47/6867 , A61K51/1027 , A61K2039/505 , C07K16/3061 , C07K2317/24 , C07K2317/34 , C07K2317/40 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/92 , G01N33/57492 , Y02A50/412 , Y02A50/423
摘要： The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
摘要翻译： 本发明涉及可用于治疗哺乳动物造血肿瘤的物质组合物，以及使用这些物质组合物的方法。
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