公开(公告)号：US09852501B2

公开(公告)日：2017-12-26

申请号：US15161679

申请日：2016-05-23

Applicant: GENERAL ELECTRIC COMPANY

Inventor： Mirabela Rusu ,  Roshni Bhagalia

IPC: G06K9/00 ,  G06T7/00 ,  G06K9/62 ,  A61B6/03 ,  A61B6/00

CPC classification number: A61B6/50 ,  A61B6/032 ,  G06K9/6228 ,  G06K9/628 ,  G06T7/0012 ,  G06T7/41 ,  G06T2207/10081 ,  G06T2207/20076 ,  G06T2207/20081 ,  G06T2207/30061

Abstract: A method of creating a diagnostic evaluation for usual interstitial pneumonia is provided, including obtaining a first plurality of series of HRCT lung slices indicating the presence of UIP, obtaining an identification of UIP and non-UIP voxels, extracting textural and localization features from the UIP and non-UIP voxels, selecting features that are more accurate in differentiating UIP voxels from non-UIP voxels than other features are, eliminating features highly correlated with a more accurate feature, and constructing a predictive model by performing a second classifier to provide a probability that a voxel signifies the presence of UIP. Also provided is a method of identifying UIP in a subject's lung by applying a diagnostic evaluation for UIP that was created with the foregoing method.

公开(公告)号：US20190147215A1

公开(公告)日：2019-05-16

申请号：US15814511

申请日：2017-11-16

Applicant: General Electric Company

Inventor： Yousef Al-Kofahi ,  Mirabela Rusu

IPC: G06K9/00 ,  G06T7/00 ,  G06T7/11

CPC classification number: G06K9/0014 ,  G06K9/00134 ,  G06T7/0012 ,  G06T7/0014 ,  G06T7/11 ,  G06T7/136 ,  G06T7/143 ,  G06T7/194 ,  G06T2207/10056 ,  G06T2207/10064 ,  G06T2207/20021 ,  G06T2207/20076 ,  G06T2207/20081 ,  G06T2207/20152 ,  G06T2207/20156 ,  G06T2207/30024

Abstract: The present disclosure relates to a computer-implemented system and its associated method for single channel whole cell segmentation of a sample image of a biological sample. The biological sample may be stained with one or more non-nuclear cell marker stains, and the system and the method are configured to transform the sample image of the biological sample stained with the one or more non-nuclear cell marker stains into a segmented image having one or more cells with delineated nuclei and cytoplasm regions.

公开(公告)号：US20190005640A1

公开(公告)日：2019-01-03

申请号：US15640909

申请日：2017-07-03

Applicant: General Electric Company

Inventor： Dattesh Dayanand Shanbhag ,  Mirabela Rusu ,  Sandeep Narendra Gupta

IPC: G06T7/00 ,  G01R33/48 ,  A61B5/055 ,  A61B6/03 ,  A61B8/08 ,  A61B6/00 ,  A61B8/00 ,  A61B5/00

Abstract: The disclosed approach employs a generic methodology for transforming individual modality specific multi-parametric data into data, e.g., maps or images, which provides direct insight into the underlying physiology of the tissue. This may facilitate better clinical evaluation of the disease data as well as help non-imaging technologists and scientist to directly correlate imaging findings with basic biological phenomenon being studied with imaging.