公开(公告)号：US20140275962A1

公开(公告)日：2014-09-18

申请号：US13797395

申请日：2013-03-12

Applicant: GENERAL ELECTRIC COMPANY

Inventor： Thomas Kwok-Fah Foo ,  Lowell Scott Smith ,  Kai Erik Thomenius ,  Sandeep Narendra Gupta ,  Luca Marinelli ,  Kedar Anil Patwardhan ,  Dominic Michael Graziani

IPC: A61N2/00

CPC classification number: A61N2/002 ,  A61B5/0035 ,  H05K999/99

Abstract: Methods and systems using magnetic resonance and ultrasound for tracking anatomical targets for radiation therapy guidance are provided. One system includes a patient transport configured to move a patient between and into a magnetic resonance (MR) system and a radiation therapy (RT) system and an ultrasound transducer coupled to the patient transport, wherein the ultrasound transducer is configured to acquire four-dimensional (4D) ultrasound images concurrently with one of an MR acquisition or an RT radiation therapy session. The system also includes a controller having a processor configured to use the 4D ultrasound images and MR images from the MR system to control at least one of a photon beam spatial distribution or intensity modulation generated by the RT system.

Abstract translation: 提供了使用磁共振和超声波跟踪放射治疗指导解剖靶标的方法和系统。 一种系统包括被配置为将患者移动到磁共振（MR）系统和辐射治疗（RT）系统之间的患者输送和耦合到患者输送的超声换能器，其中超声换能器被配置为获取四维 （4D）超声图像与MR采集或RT放射治疗会话之一同时进行。 该系统还包括具有处理器的控制器，其被配置为使用来自MR系统的4D超声图像和MR图像来控制RT系统产生的光子束空间分布或强度调制中的至少一个。

公开(公告)号：US20160310082A1

公开(公告)日：2016-10-27

申请号：US15101538

申请日：2014-09-05

Applicant: General Electric Company

Inventor： Kumar Rajamani ,  Sandeep Narendra Gupta ,  Rakesh Mullick ,  Dattesh Dayanand Shanbhag

IPC: A61B5/00 ,  A61B6/03 ,  A61B5/02 ,  A61B6/00 ,  G06T7/20 ,  A61B8/00 ,  G01R33/56 ,  G01R33/565 ,  G01R33/48 ,  G06T7/00 ,  A61B5/055 ,  A61B8/08

CPC classification number: A61B5/7207 ,  A61B5/0044 ,  A61B5/055 ,  A61B5/1128 ,  A61B5/7289 ,  A61B6/032 ,  A61B6/037 ,  A61B6/5264 ,  A61B8/5276 ,  A61B2576/00 ,  G01R33/5601 ,  G01R33/5608 ,  G01R33/56308 ,  G01R33/56509

Abstract: A system and method for detecting motion is presented. The system and method includes identifying a region of interest in the plurality of images corresponding to a subject of interest. Furthermore, the system and method includes determining signal characteristics corresponding to the region of interest. In addition, the system and method includes generating a composite signal, where the composite signal comprises an aggregate of the signal characteristics corresponding to the region of interest. The system and method also includes analyzing the composite signal to detect motion in the region of interest.

Abstract translation: 提出了一种用于检测运动的系统和方法。 该系统和方法包括识别与感兴趣对象相对应的多个图像中的感兴趣区域。 此外，该系统和方法包括确定对应于感兴趣区域的信号特性。 此外，该系统和方法包括生成复合信号，其中复合信号包括对应于感兴趣区域的信号特征的聚合。 该系统和方法还包括分析复合信号以检测感兴趣区域中的运动。

公开(公告)号：US10806947B2

公开(公告)日：2020-10-20

申请号：US15277198

申请日：2016-09-27

Applicant: GENERAL ELECTRIC COMPANY

Inventor： Thomas Kwok-Fah Foo ,  Lowell Scott Smith ,  Kai Erik Thomenius ,  Sandeep Narendra Gupta ,  Luca Marinelli ,  Kedar Anil Patwardhan ,  Dominic Michael Graziani

IPC: A61B5/00 ,  A61N5/10 ,  A61B5/055 ,  A61B8/08 ,  A61B5/113

Abstract: Methods and systems using magnetic resonance and ultrasound for tracking anatomical targets for radiation therapy guidance are provided. One system includes a patient transport configured to move a patient between and into a magnetic resonance (MR) system and a radiation therapy (RT) system. An ultrasound transducer is also provided that is hands-free and electronically steerable, securely attached to the patient, such that the ultrasound transducer is configured to acquire four-dimensional (4D) ultrasound images concurrently with one of an MR acquisition or an RT radiation therapy session. The system also includes a controller having a processor configured to use the 4D ultrasound images and MR images from the MR system to control at least one of a photon beam spatial distribution or intensity modulation generated by the RT system. The system determines the previously-acquired correct MR images that represent a specific motion state at some time, t, by a plurality of transformations that allow the representation of the position of fiducial markers in the corresponding ultrasound images to match that of a prior ultrasound acquisition.

公开(公告)号：US10362992B2

公开(公告)日：2019-07-30

申请号：US15101538

申请日：2014-09-05

Applicant: General Electric Company

Inventor： Kumar Rajamani ,  Sandeep Narendra Gupta ,  Rakesh Mullick ,  Dattesh Dayanand Shanbhag

IPC: A61B5/055 ,  A61B5/00 ,  A61B6/00 ,  A61B8/08 ,  G01R33/565 ,  A61B5/11 ,  A61B6/03 ,  G01R33/56 ,  G01R33/563

Abstract: A system and method for detecting motion is presented. The system and method includes identifying a region of interest in the plurality of images corresponding to a subject of interest. Furthermore, the system and method includes determining signal characteristics corresponding to the region of interest. In addition, the system and method includes generating a composite signal, where the composite signal comprises an aggregate of the signal characteristics corresponding to the region of interest. The system and method also includes analyzing the composite signal to detect motion in the region of interest.

公开(公告)号：US20190005640A1

公开(公告)日：2019-01-03

申请号：US15640909

申请日：2017-07-03

Applicant: General Electric Company

Inventor： Dattesh Dayanand Shanbhag ,  Mirabela Rusu ,  Sandeep Narendra Gupta

IPC: G06T7/00 ,  G01R33/48 ,  A61B5/055 ,  A61B6/03 ,  A61B8/08 ,  A61B6/00 ,  A61B8/00 ,  A61B5/00

Abstract: The disclosed approach employs a generic methodology for transforming individual modality specific multi-parametric data into data, e.g., maps or images, which provides direct insight into the underlying physiology of the tissue. This may facilitate better clinical evaluation of the disease data as well as help non-imaging technologists and scientist to directly correlate imaging findings with basic biological phenomenon being studied with imaging.

公开(公告)号：US20170014645A1

公开(公告)日：2017-01-19

申请号：US15277198

申请日：2016-09-27

Applicant: GENERAL ELECTRIC COMPANY

Inventor： Thomas Kwok-Fah Foo ,  Lowell Scott Smith ,  Kai Erik Thomenius ,  Sandeep Narendra Gupta ,  Luca Marinelli ,  Kedar Anil Patwardhan ,  Dominic Michael Graziani

IPC: A61N5/10 ,  A61B5/113 ,  A61B5/00 ,  A61B5/055 ,  A61B8/08

Abstract: Methods and systems using magnetic resonance and ultrasound for tracking anatomical targets for radiation therapy guidance are provided. One system includes a patient transport configured to move a patient between and into a magnetic resonance (MR) system and a radiation therapy (RT) system. An ultrasound transducer is also provided that is hands-free and electronically steerable, securely attached to the patient, such that the ultrasound transducer is configured to acquire four-dimensional (4D) ultrasound images concurrently with one of an MR acquisition or an RT radiation therapy session. The system also includes a controller having a processor configured to use the 4D ultrasound images and MR images from the MR system to control at least one of a photon beam spatial distribution or intensity modulation generated by the RT system. The system determines the previously-acquired correct MR images that represent a specific motion state at some time, t, by a plurality of transformations that allow the representation of the position of fiducial markers in the corresponding ultrasound images to match that of a prior ultrasound acquisition.

Abstract translation: 提供了使用磁共振和超声波跟踪放射治疗指导解剖靶标的方法和系统。 一个系统包括被配置为将患者移动到磁共振（MR）系统和放射治疗（RT）系统之间）的患者输送。 还提供了一种超声换能器，其是免提的并且可电子操纵的，牢固地附接到患者，使得超声换能器被配置为与MR采集或RT放射治疗之一同时获取四维（4D）超声图像 会话 该系统还包括具有处理器的控制器，其被配置为使用来自MR系统的4D超声图像和MR图像来控制RT系统产生的光子束空间分布或强度调制中的至少一个。 该系统通过允许在对应的超声图像中的基准标记的位置的表示与先前的超声波获取相匹配的多个变换来确定在某时刻t表示特定运动状态的先前获得的正确MR图像 。