公开(公告)号：US11512288B2

公开(公告)日：2022-11-29

申请号：US16339077

申请日：2017-08-24

Applicant: General Electric Company

Inventor： Ernest William Kovacs ,  Anup Sood ,  Reginald Donovan Smith ,  Evelina Roxana Loghin ,  Padmaparna Chaudhuri ,  Vandana Keskar ,  Chrystal Mae Chadwick ,  Martin James Brown

IPC: C12N5/0783 ,  C07K16/28

Abstract: Provided herein are methods of activating immune cells. The method includes providing a population of immune cells and contacting the population of immune cells with a first agent and a second agent. The first agent includes an immune cell activator attached to a first binder moiety, and the second agent includes at least one capture oligomer. The at least one capture oligomer is capable of associating with the first binder moiety. Also provided are kits for activating immune cells.

公开(公告)号：US20200181572A1

公开(公告)日：2020-06-11

申请号：US16339077

申请日：2017-08-24

Applicant: General Electric Company

Inventor： Ernest William Kovacs ,  Anup Sood ,  Reginald Donovan Smith ,  Evelina Roxana Loghin ,  Padmaparna Chaudhuri ,  Vandana Keskar ,  Chrystal Mae Chadwick ,  Martin James Brown

IPC: C12N5/0783 ,  C07K16/28

Abstract: Provided herein are methods of activating immune cells. The method includes providing a population of immune cells and contacting the population of immune cells with a first agent and a second agent. The first agent includes an immune cell activator attached to a first binder moiety, and the second agent includes at least one capture oligomer. The at least one capture oligomer is capable of associating with the first binder moiety. Also provided are kits for activating immune cells.