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公开(公告)号:US20240216313A1
公开(公告)日:2024-07-04
申请号:US18289213
申请日:2022-05-10
申请人: Genfit
发明人: Vanessa Legry , Remy Hanf , Simon Debaecker , Philippe Poulain , Benoit Noel , Robert Walczak , Peggy Parroche
IPC分类号: A61K31/192 , A61K31/407 , A61P31/00
CPC分类号: A61K31/192 , A61K31/407 , A61P31/00
摘要: The invention relates to compounds for use in the treatment of sepsis.
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公开(公告)号:US11484517B2
公开(公告)日:2022-11-01
申请号:US16606235
申请日:2018-04-18
申请人: GENFIT
发明人: Robert Walczak , Carole Belanger , Vanessa Legry , Benoît Noel , Emeline Descamps , Guillaume Vidal , Mathilde Walczak , Isabelle Delbaere
IPC分类号: A61K31/192 , A61P1/16 , A61K31/166 , A61K31/198 , A61K31/426 , A61K31/437 , A61K31/4402 , A61K31/4439 , A61K31/506 , A61K31/519 , A61K31/52 , A61K31/53 , A61K31/538 , A61K31/575 , A61K31/662 , A61K31/194 , A61K31/438 , A61K31/444 , A61K31/5377
摘要: The present invention relates to a combination product and its use in therapy.
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公开(公告)号:US20220133716A1
公开(公告)日:2022-05-05
申请号:US17494458
申请日:2021-10-05
申请人: Genfit
发明人: Jean-Francois Delhomel , Enrico Perspicace , Zouher Majd , Peggy Parroche , Robert Walczak , Pascal Bonnet , Jade Fogha
IPC分类号: A61K31/496 , A61K31/192 , C07D405/14 , A61K31/506 , A61K31/4184 , A61K31/4439 , A61K31/40
摘要: The present invention provides novel compounds that are modulators of RORgamma. These compounds, and pharmaceutical compositions comprising the same, are suitable means for treating any disease wherein the modulation of RORgamma has therapeutic effects, for instance in autoimmune diseases, autoimmune-related diseases, inflammatory diseases, metabolic diseases, fibrotic diseases, or cholestatic diseases.
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公开(公告)号:US20200054589A1
公开(公告)日:2020-02-20
申请号:US16484988
申请日:2018-02-21
申请人: Genfit
发明人: Benoît Noel , Robert Walczak , Carole Belanger
IPC分类号: A61K31/192 , A61K31/575 , A61P1/16 , A61P29/00
摘要: The present invention relates to a combination of active ingredients for use in the treatment of diseases.
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公开(公告)号:US20190388414A1
公开(公告)日:2019-12-26
申请号:US16481172
申请日:2018-01-29
申请人: Genfit
发明人: Jean-Francois Delhomel , Enrico Perspicace , Zouher Majd , Peggy Parroche , Robert Walczak , Pascal Bonnet , Jade Fogha
IPC分类号: A61K31/496 , C07D405/14 , A61K31/506 , A61K31/192 , A61K31/40 , A61K31/4184 , A61K31/4439
摘要: The present invention provides novel compounds that are modulators of RORgamma. These compounds, and pharmaceutical compositions comprising the same, are suitable means for treating any disease wherein the modulation of RORgamma has therapeutic effects, for instance in autoimmune diseases, autoimmune-related diseases, inflammatory diseases, metabolic diseases, fibrotic diseases, or cholestatic diseases.
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公开(公告)号:US11160801B2
公开(公告)日:2021-11-02
申请号:US16481172
申请日:2018-01-29
申请人: Genfit
发明人: Jean-Francois Delhomel , Enrico Perspicace , Zouher Majd , Peggy Parroche , Robert Walczak , Pascal Bonnet , Jade Fogha
IPC分类号: C07D405/14 , A61K31/496 , A61K31/192 , A61K31/40 , A61K31/4184 , A61K31/4439 , A61K31/506
摘要: The present invention provides novel compounds that are modulators of RORgamma. These compounds, and pharmaceutical compositions comprising the same, are suitable means for treating any disease wherein the modulation of RORgamma has therapeutic effects, for instance in autoimmune diseases, autoimmune-related diseases, inflammatory diseases, metabolic diseases, fibrotic diseases, or cholestatic diseases.
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公开(公告)号:US10905680B2
公开(公告)日:2021-02-02
申请号:US16209660
申请日:2018-12-04
申请人: Genfit
发明人: Raphael Darteil , Robert Walczak , Carole Belanger , Emilie Negro , Pierre Daubersies , Philippe Delataille
IPC分类号: A61K31/426 , A61K45/06
摘要: The present invention relates to the compound [2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl]ethanoate (Nitazoxanide) or 2-hydroxy-N-(5-nitro-2-thiazolyl)benzamide (Tizoxanide) for treating cholestatic and fibrotic diseases.
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公开(公告)号:US20190388394A1
公开(公告)日:2019-12-26
申请号:US16485025
申请日:2018-02-23
申请人: Genfit
发明人: Emeline Descamps , Robert Walczak , Carole Belanger , Benoît Noel
IPC分类号: A61K31/4178 , A61K31/192 , A61P1/16
摘要: The present invention relates to a combination of active ingredients for use in the treatment of diseases.
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公开(公告)号:US09902725B2
公开(公告)日:2018-02-27
申请号:US15539519
申请日:2015-12-22
申请人: GENFIT
发明人: Jean-Francois Delhomel , Robert Walczak , Zouher Majd , Emilie Pihan , Pascal Bonnet , Enrico Perspicace
IPC分类号: C07D471/04 , C07D401/12 , C07D403/12 , C07D209/20 , C07D401/14
CPC分类号: C07D471/04 , C07D209/18 , C07D209/20 , C07D231/56 , C07D401/12 , C07D401/14 , C07D403/12
摘要: The present invention provides novel compounds of formula (I) that are modulators of RORgamma. These compounds, and pharmaceutical compositions comprising the same, are suitable means for treating any disease wherein the modulation of RORgamma has therapeutic effects, for instance in autoimmune diseases, autoimmune-related diseases, inflammatory diseases, fibrotic diseases, or cholestatic diseases.
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10.
公开(公告)号:US11478440B2
公开(公告)日:2022-10-25
申请号:US16606233
申请日:2018-04-18
申请人: GENFIT
发明人: Robert Walczak , Carole Belanger , Vanessa Legry , Benoît Noel , Emeline Descamps , Guillaume Vidal , Mathilde Walczak
IPC分类号: A61K31/192 , A61P1/16 , A61K31/166 , A61K31/198 , A61K31/426 , A61K31/437 , A61K31/4402 , A61K31/4439 , A61K31/506 , A61K31/519 , A61K31/52 , A61K31/53 , A61K31/538 , A61K31/575 , A61K31/662 , A61K31/194 , A61K31/438 , A61K31/444 , A61K31/5377
摘要: The present invention relates to a combination product and its use in therapy.
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