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公开(公告)号:US10227645B2
公开(公告)日:2019-03-12
申请号:US15274770
申请日:2016-09-23
Applicant: Genia Technologies, Inc.
Inventor: Timothy Kellogg Craig , Cynthia Ann Cech , Michael Dorwart , Liv Elisabeth Jensen , Marshall Winston Porter , Christos Tzitzilonis , Alexander Hyun-min Yang
IPC: C07K14/31 , C12Q1/6869
Abstract: Described herein are engineered alpha-hemolysin subunits having mutated oligomerization domains for assembling into heptameric nanopores in lipid bilayers.