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公开(公告)号：US20190030178A1
公开(公告)日：2019-01-31
申请号：US15758520
申请日：2016-09-09
Applicant: GENMAB A/S
Inventor： Steen LISBY , Nancy Cherry WHITING
Abstract: Anti-TF antibody drug conjugate and pharmaceutical compositions comprising the antibody drug-conjugate for use in the treatment of a solid cancer comprising administering to a subject a weekly dose of from about 0.8 mg/kg to about 1.8 mg/kg of an anti-TF antibody drug conjugate once a week for three consecutive weeks followed by a one week resting period without any administration of anti-TF ADC so that each cycle time is 28 days including the resting period.
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公开(公告)号：US20220265844A1
公开(公告)日：2022-08-25
申请号：US17548436
申请日：2021-12-10
Applicant: Genmab A/S
Inventor： Steen LISBY , Nancy Cherry WHITING
Abstract: Anti-TF antibody drug conjugate and pharmaceutical compositions comprising the antibody drug-conjugate for use in the treatment of a solid cancer comprising administering to a subject a weekly dose of from about 0.8 mg/kg to about 1.8 mg/kg of an anti-TF antibody drug conjugate once a week for three consecutive weeks followed by a one week resting period without any administration of anti-TF ADC so that each cycle time is 28 days including the resting period.
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