公开(公告)号：US20180135082A1

公开(公告)日：2018-05-17

申请号：US15564327

申请日：2016-04-07

Applicant: Genomatica, Inc.

Inventor： Stephanie J. Culler ,  Nicholas Eakley ,  Kevin Gregory Hoff ,  Robin E. Osterhout ,  Priti Pharkya ,  Erik C. Ralph ,  Stephen Van Dien

IPC: C12P5/02 ,  C12P7/16 ,  C12N9/04 ,  C12N9/02

CPC classification number: C12P5/026 ,  C12N9/0006 ,  C12N9/001 ,  C12P7/04 ,  C12P7/16 ,  Y02E50/10

Abstract: Disclosed are methods and engineered microorganisms that enhance or improve the production of crotyl alcohol. The engineered microorganisms include genetic modifications in alcohol dehydrogenase, alkene reductase or both enzymatic activities. By such genetic modifications, a crotyl alcohol production pathway is provided or improved.

公开(公告)号：US20210277426A1

公开(公告)日：2021-09-09

申请号：US16953050

申请日：2020-11-19

Applicant: Genomatica, Inc.

Inventor： Stephanie J. Culler ,  Nicholas Eakley ,  Kevin Gregory Hoff ,  Robin E. Osterhout ,  Priti Pharkya ,  Erik C. Ralph ,  Stephen J. Van Dien

IPC: C12P5/02 ,  C12N9/04 ,  C12N9/02 ,  C12P7/16 ,  C12P7/04

Abstract: Disclosed are methods and engineered microorganisms that enhance or improve the production of crotyl alcohol. The engineered microorganisms include genetic modifications in alcohol dehydrogenase, alkene reductase or both enzymatic activities. By such genetic modifications, a crotyl alcohol production pathway is provided or improved.