公开(公告)号：US4742169A

公开(公告)日：1988-05-03

申请号：US720447

申请日：1985-04-05

申请人： Marsha A. Paul ,  George A. Doorakian

发明人： Marsha A. Paul ,  George A. Doorakian

IPC分类号： C07D295/205 ,  C07D303/16 ,  C07D241/04

CPC分类号： C07D295/205 ,  C07D303/16

摘要： The invention is a process for the preparation of halohydroxyalkyl carbamates which comprises contacting an epihalohydrin carbonate with a secondary amine-containing compound, wherein the secondary amine has a pKa at which the secondary amine will react with the epihalohydrin carbonate and which does not catalyze the formation of unwanted by-products in the further presence of an acid scavenger capable of forming a salt with the hydrogen halide by-product formed, in an amount sufficient to prevent the formation of unwanted by-products, in a polar organic solvent under conditions such that a halohydroxyalkyl carbamate, wherein the carbamate nitrogen is tertiary, is prepared.Another aspect of this invention is the further step of contacting the 3-halo-2-hydroxyalkyl carbamate with an ion-exchange resin with pendant moieties containing hydroxide moieties in a lower alkanol solvent under conditions such that the 3-halo-2-hydroxyalkyl moieties are converted to 2,3-epoxyalkyl moieties so as to prepare a 2,3-epoxyalkyl carbamate.

摘要翻译： 本发明是制备卤代羟烷基氨基甲酸酯的方法，其包括使表卤代醇碳酸酯与含仲胺的化合物接触，其中仲胺具有pKa，其中仲胺将与表卤代醇碳酸酯反应并且不催化形成 的不需要的副产物在酸性清除剂的进一步存在下，能够形成与卤化氢副产物形成的盐，其量足以防止不想要的副产物在极性有机溶剂中形成，条件是使得 制备其中氨基甲酸氮为叔的卤代羟烷基氨基甲酸酯。 本发明的另一方面是使3-卤代-2-羟基烷基氨基甲酸酯与离子交换树脂与在低级链烷醇溶剂中含有氢氧化物部分的侧基部分接触的步骤，使得3-卤代-2-羟基烷基部分 转化为2,3-环氧烷基部分，以制备氨基甲酸2,3-环氧烷基酯。

公开(公告)号：US4613661A

公开(公告)日：1986-09-23

申请号：US738325

申请日：1985-05-28

申请人： Horst G. Langer ,  Thomas P. Brady ,  Marsha A. Paul ,  George A. Doorakian

发明人： Horst G. Langer ,  Thomas P. Brady ,  Marsha A. Paul ,  George A. Doorakian

IPC分类号： C07F9/655 ,  C08G59/14 ,  C08G59/30 ,  C09D5/18 ,  C09D163/00

CPC分类号： C08G59/1488 ,  C07F9/65502 ,  C08G59/304 ,  C09D5/185

摘要： A process for preparing a phosphate ester which contains at least one terminal epoxide moiety, the process comprising contacting under reaction conditions, optionally in the presence of water, at least one phosphoric acid ester with an amount of an epoxide having an epoxy equivalent greater than one. The product compositions can be cured by standard epoxide curing agents to provide protective coatings having intumescent properties.

摘要翻译： 一种制备含有至少一个末端环氧化物部分的磷酸酯的方法，该方法包括任选在水存在下在反应条件下，与至少一种具有环氧当量大于1的环氧化合物的磷酸酯接触 。 产品组合物可以通过标准环氧化物固化剂固化，以提供具有膨胀特性的保护涂层。

公开(公告)号：US4496709A

公开(公告)日：1985-01-29

申请号：US504918

申请日：1983-06-16

申请人： George A. Doorakian ,  Marsha A. Paul ,  Adolphus V. Gist

发明人： George A. Doorakian ,  Marsha A. Paul ,  Adolphus V. Gist

IPC分类号： C08G59/02 ,  C08G59/06 ,  C08G59/68

CPC分类号： C08G59/066 ,  C08G59/02 ,  C08G59/688

摘要： Epoxy resins having improved properties are prepared by reacting an epoxy resin with a dihydric phenol in the presence of a sufficient quantity of a phosphonium trifluoroacetate catalyst such that the product resulting from reacting a mixture of the catalyst, epoxy resin and dihydric phenol has a % epoxide difference from the theoretical percent epoxide of from about 0.5 to about 4.0.

摘要翻译： 具有改善性能的环氧树脂通过使环氧树脂与二元酚在足够量的三氟乙酸鏻催化剂存在下反应制备，使得由催化剂，环氧树脂和二元酚的混合物反应得到的产物具有％环氧化物 与理论环氧化物的差异为约0.5至约4.0。

公开(公告)号：US4438254A

公开(公告)日：1984-03-20

申请号：US470107

申请日：1983-02-28

申请人： George A. Doorakian ,  Marsha A. Paul

发明人： George A. Doorakian ,  Marsha A. Paul

IPC分类号： C08G59/62 ,  C08G59/00 ,  C08G59/02 ,  C08G59/06 ,  C08G59/14 ,  C08G59/68 ,  C08L63/00

CPC分类号： C08G59/066 ,  C08G59/02

摘要： An improved process for reacting vicinal epoxides with phenols or thiophenols is described. This process is conducted at essentially anhydrous conditions and temperatures less than 175.degree. C. The resulting resins are generally more linear and less colored than advanced resins produced via prior art processes. Also the phosphonium catalyst remains active to promote subsequent advancement or curing reactions. The catalyst can be deactivated in a separate step to produce a resin of exceptional purity.

摘要翻译： 描述了使邻位环氧化物与苯酚或苯硫酚反应的改进方法。 该方法在基本上无水条件和低于175℃的温度下进行。所得到的树脂通常比通过现有技术方法生产的先进树脂更线性且颜色少。 此外，鏻催化剂保持活性以促进随后的进行或固化反应。 催化剂可以在单独的步骤中失活以产生特别纯度的树脂。

公开(公告)号：US4897352A

公开(公告)日：1990-01-30

申请号：US144205

申请日：1988-01-15

申请人： Yohannes Chonde ,  Marsha A. Paul

发明人： Yohannes Chonde ,  Marsha A. Paul

IPC分类号： C12N11/08

CPC分类号： C12N11/08

摘要： Enzymes are immobilized on macroporous hydrophilic polymer beads by adsorption. The polymer beads are cross-linked, acrylate-based resins containing pendant hydroxy groups. The resins contain 10-70% methyl methacrylate, 10-70% methylacrylate, 5-14 40% ethylenically unsaturated monomer having at least one pendant hydroxyl group and 10-25% divinylbenzene. The resins provide immobilized enzyme preparations exhibiting excellent physical strength and stability as well as high enzyme activity.

摘要翻译： 通过吸附将酶固定在大孔亲水聚合物珠上。 聚合物珠粒是含有侧基羟基的交联的丙烯酸酯类树脂。 树脂含有10-70％甲基丙烯酸甲酯，10-70％甲基丙烯酸酯，5-14 40％具有至少一个侧基羟基的烯属不饱和单体和10-25％的二乙烯基苯。 树脂提供显示出优异的物理强度和稳定性以及高酶活性的固定化酶制剂。