公开(公告)号：US20070043014A1

公开(公告)日：2007-02-22

申请号：US10571334

申请日：2004-09-27

申请人： George Doherty ,  Jeffrey Hale ,  Irene Legiec ,  Christopher Lynch ,  Leslie Toth

发明人： George Doherty ,  Jeffrey Hale ,  Irene Legiec ,  Christopher Lynch ,  Leslie Toth

IPC分类号： A61K31/506 ,  A61K31/501 ,  A61K31/497 ,  A61K31/4709 ,  A61K31/4745 ,  A61K31/4439 ,  A61K31/4245 ,  C07D413/04

CPC分类号： C07D413/04 ,  C07D271/06

摘要： The present invention encompasses compounds of Formula I: (I) as well as the pharmaceutically acceptable salts thereof. The compounds are useful for treating immune mediated diseases and conditions, such as bone marrow, organ and tissue transplant rejection. Pharmaceutical compositions and methods of use are included.

摘要翻译： 本发明包括式I化合物：（I）及其药学上可接受的盐。 该化合物可用于治疗免疫介导的疾病和病症，例如骨髓，器官和组织移植排斥反应。 包括药物组合物和使用方法。

公开(公告)号：US5282938A

公开(公告)日：1994-02-01

申请号：US835601

申请日：1992-02-13

申请人： Irene Legiec ,  David S. Kosson ,  Jean-Luc Ontiveros ,  Tracey L. Clapp

发明人： Irene Legiec ,  David S. Kosson ,  Jean-Luc Ontiveros ,  Tracey L. Clapp

IPC分类号： B09B3/00 ,  C22B7/02 ,  C22B13/02 ,  C25C1/00

CPC分类号： C22B7/02 ,  B09B3/00 ,  C22B13/025 ,  B09B2220/06 ,  Y02P10/214

摘要： A method for the continuous treatment of air pollution control residues from various resource recovery systems whereby the air pollution control residue is treated with a dilute salt extracting solution at a pH chosen to maximize the recovery of lead, for a reaction time chosen to maximize the recovery of lead, and for a number of recycles chosen to maximize the recovery of lead from the particular residue being treated. Other metals and dissolved salts can also be recovered from the extracting solution. Thus by monitoring these three variables for each batch of residue, and adjusting the extracting solution accordingly, residue from various sources and of varying composition can be treated efficiently and continuously to remove hazardous metals and dissolved salts from the residue. Bottom residue fines, alone or admixed with air pollution control residues, can also be treated in accordance with the process of the invention.

摘要翻译： 一种用于连续处理来自各种资源回收系统的空气污染控制残留物的方法，其中空气污染控制残留物用选择的pH选择以使铅的回收最大化的稀盐提取溶液处理，以选择最大化回收的反应时间 的铅，以及一些回收利用，以最大限度地从被处理的特定残留物中回收铅。 其他金属和溶解的盐也可以从萃取溶液中回收。 因此，通过监测每批残渣的这三个变量，并相应调整萃取液，可以有效和连续地处理各种来源和不同成分的残留物，从残留物中除去有害金属和溶解的盐。 单独的或与空气污染控制残留物混合的底部残留物也可以根据本发明的方法进行处理。