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公开(公告)号：US5985259A
公开(公告)日：1999-11-16
申请号：US846406
申请日：1997-04-30
IPC分类号： A61K9/00 , A61K31/496 , A61K31/70 , A61K31/74
CPC分类号： A61K31/496 , A61K9/0048
摘要： An improved method of sterilizing the field of surgery prior to an ophthalmic surgical procedure is described. The invention eliminates the need for painfull and potentially traumatic injections of antibiotics by utilizing sustained release compositions which allow the antibiotics contained therein to penetrate deeply into the eye, thereby ensuring a sterile field of surgery during intraocular surgical procedures. The compositions may also be utilized to prevent post-surgical infections.
摘要翻译： 描述了在眼外科手术之前对手术领域进行消毒的改进方法。 本发明通过使用允许其中包含的抗生素深入眼睛的持续释放组合物消除了对抗生素的疼痛和潜在创伤性注射抗生素的需要，从而确保了眼内手术过程中的无菌手术领域。 组合物也可用于预防手术后感染。
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2.发明授权Use of sustained release antibiotic compositions in ophthalmic surgical procedures 失效缓释抗生素组合物在眼科手术中的应用公开(公告)号：US06630135B1
公开(公告)日：2003-10-07
申请号：US09438987
申请日：1999-11-12
IPC分类号： A61K3170
CPC分类号： A61K31/496 , A61K9/0048
摘要： An improved method of sterilizing the field of surgery prior to an ophthalmic surgical procedure is described. The invention eliminates the need for painful and potentially traumatic injections of antibiotics by utilizing sustained release compositions which allow the antibiotics contained therein to penetrate deeply into the eye, thereby ensuring a sterile field of surgery during intraocular surgical procedures. The compositions may also be utilized to prevent post-surgical infections.
摘要翻译： 描述了在眼外科手术之前对手术领域进行消毒的改进方法。 本发明通过使用允许其中包含的抗生素深入眼睛的持续释放组合物消除了对抗生素疼痛和潜在创伤性注射抗生素的需要，从而确保了眼内手术过程中的无菌手术领域。 组合物也可用于预防手术后感染。
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3.发明授权Use of sustained release antibiotic compositions in ophthalmic surgical procedures 失效缓释抗生素组合物在眼科手术中的应用
公开(公告)号：US5631004A
公开(公告)日：1997-05-20
申请号：US129924
申请日：1993-09-30
IPC分类号： A61K9/00 , A61K31/496 , A61K31/70 , A61K31/74
CPC分类号： A61K31/496 , A61K9/0048
摘要： An improved method of sterilizing the field of surgery prior to an ophthalmic surgical procedure is described. The invention eliminates the need for painful and potentially traumatic injections of antibiotics by utilizing sustained release compositions which allow the antibiotics contained therein to penetrate deeply into the eye, thereby ensuring a sterile field of surgery during intraocular surgical procedures. The compositions may also be utilized to prevent post-surgical infections.
摘要翻译： 描述了在眼外科手术之前对手术领域进行消毒的改进方法。 本发明通过使用允许其中包含的抗生素深入眼睛的持续释放组合物消除了对抗生素疼痛和潜在创伤性注射抗生素的需要，从而确保了眼内手术过程中的无菌手术领域。 组合物也可用于预防手术后感染。
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公开(公告)号：US5409904A
公开(公告)日：1995-04-25
申请号：US977312
申请日：1992-11-16
申请人： Gerald Hecht , Ole J. Lorenzetti
发明人： Gerald Hecht , Ole J. Lorenzetti
CPC分类号： A61L31/041 , A61K9/0048 , A61L31/042 , A61L2430/16
摘要： Disclosed are solutions useful in surgery comprising a viscous or viscoelastic substance in an aqueous vehicle which is characterized as physiologically compatible; also disclosed are methods of using such solutions, implanting such viscous or viscoelastic substances, while minimizing the traumatic effect of surgery at the cellular level.
摘要翻译： 公开了一种在手术中有用的溶液，其包含在水性载体中的粘性或粘弹性物质，其特征在于生理上相容; 还公开了使用这种溶液的方法，植入这样的粘性或粘弹性物质，同时最小化手术在细胞水平的创伤作用。
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公开(公告)号：US5578578A
公开(公告)日：1996-11-26
申请号：US425132
申请日：1995-04-19
申请人： Gerald Hecht , Ole J. Lorenzetti
发明人： Gerald Hecht , Ole J. Lorenzetti
CPC分类号： A61L31/041 , A61K9/0048 , A61L31/042 , A61L2430/16
摘要： Disclosed are solutions useful in surgery comprising a viscous or viscoelastic substance in an aqueous vehicle which is characterized as physiologically compatible; also disclosed are methods of using such solutions, implanting such viscous or viscoelastic substances, while minimizing the traumatic effect of surgery at the cellular level.
摘要翻译： 公开了一种在手术中有用的溶液，其包含在水性载体中的粘性或粘弹性物质，其特征在于生理上相容; 还公开了使用这种溶液的方法，植入这样的粘性或粘弹性物质，同时最小化手术在细胞水平的创伤作用。
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公开(公告)号：US5523316A
公开(公告)日：1996-06-04
申请号：US264812
申请日：1994-06-23
申请人： Owen Gan , Rajni Jani , Ole J. Lorenzetti
发明人： Owen Gan , Rajni Jani , Ole J. Lorenzetti
IPC分类号： A61K9/08 , A61K9/00 , A61K31/415
CPC分类号： A61K9/0048 , Y10S514/912
摘要： Improved ophthalmic irrigating solutions are described. The solutions include one or more drugs for controlling intraocular pressure, an antioxidant/free radical scavenger, electrolytes, a cellular energy source, bicarbonate, and a buffer. Methods of using the solutions in connection with ophthalmic surgical procedures are also described.
摘要翻译： 描述了改进的眼科冲洗溶液。 该溶液包括一种或多种用于控制眼压的药物，抗氧化剂/自由基清除剂，电解质，细胞能量源，碳酸氢盐和缓冲液。 还描述了使用与眼科手术相关的方案的方法。
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公开(公告)号：US5273056A
公开(公告)日：1993-12-28
申请号：US897733
申请日：1992-06-12
CPC分类号： A61L31/047 , A61K9/0048 , A61L31/041 , A61L31/042 , A61L31/044 , A61L31/048 , A61L2430/16
摘要： A method for conducting ocular surgery using different viscoelastic agents is disclosed.
摘要翻译： 公开了一种使用不同粘弹剂进行眼外科手术的方法。
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