公开(公告)号：US20250066328A1

公开(公告)日：2025-02-27

申请号：US18784100

申请日：2024-07-25

Applicant: Gilead Sciences, Inc.

Inventor： Jonah J. Chang ,  Jayaraman Chandrasekhar ,  Kevin S. Currie ,  Stephen D. Holmbo ,  Jesse M. Jacobsen ,  David L. Kukla ,  Seung H. Lee ,  Yasamin Moazami ,  Leena B. Patel ,  Thomas J. Paul ,  Stephane Perreault ,  Patrick J. Salvo ,  Jennifer A. Treiberg ,  Heath A. Weaver

IPC: C07D401/14 ,  A61K9/00 ,  A61K9/02 ,  A61K9/20 ,  A61K9/48 ,  A61K31/501 ,  A61K31/506 ,  A61K31/517 ,  A61K31/519 ,  A61K31/5383 ,  A61K47/02 ,  A61K47/10 ,  A61K47/12 ,  A61K47/14 ,  A61K47/26 ,  A61K47/36 ,  A61K47/38 ,  A61K47/44 ,  C07D403/14 ,  C07D413/14 ,  C07D417/14 ,  C07D471/04 ,  C07D491/048 ,  C07D498/04

Abstract: Provided herein is a compound of Formula (I): or a pharmaceutically acceptable salt, stereoisomer, mixture of stereoisomers, or deuterated analog thereof, a pharmaceutical composition comprising a compound of the present disclosure, together with a pharmaceutically acceptable excipient thereof, and a method of treating cancer with the same.

公开(公告)号：US20230365529A1

公开(公告)日：2023-11-16

申请号：US18160082

申请日：2023-01-26

Applicant: Gilead Sciences, Inc.

Inventor： Jayaraman Chandrasekhar ,  Jonah J. Chang ,  Kevin S. Currie ,  Stephen D. Holmbo ,  Jesse M. Jacobsen ,  David L. Kukla ,  Seung H. Lee ,  Yasamin Moazami ,  Leena B. Patel ,  Thomas J. Paul ,  Stephane Perreault ,  Patrick J. Salvo ,  Jennifer A. Treiberg ,  Heath A. Weaver

IPC: C07D471/04 ,  C07D405/14 ,  C07D401/14 ,  C07D487/04 ,  C07D498/04 ,  C07D413/14 ,  C07D491/107 ,  C07D495/04 ,  C07D417/14

CPC classification number: C07D401/14 ,  C07D405/14 ,  C07D413/14 ,  C07D417/14 ,  C07D471/04 ,  C07D487/04 ,  C07D491/107 ,  C07D495/04 ,  C07D498/04

Abstract: Provided herein is a compound of Formula I:





or a pharmaceutically acceptable salt, stereoisomer, mixture of stereoisomers, or deuterated analog thereof, a pharmaceutical composition comprising a compound of the present invention, together with a pharmaceutically acceptable excipient thereof, and a method of treating cancer with the same.