公开(公告)号：US10519165B2

公开(公告)日：2019-12-31

申请号：US15910744

申请日：2018-03-02

Applicant: Gilead Sciences, Inc.

Inventor： Michael Geier ,  Norihiro Ikemoto ,  Sean Liew ,  Mark E. Scott ,  Vimal Varghese

IPC: C07D309/12 ,  C07D495/04 ,  C07D493/10 ,  A61P3/00 ,  C12P7/42

Abstract: The present disclosure provides solid forms, including a salt or co-crystal, of Compound I: which exhibits Acetyl-CoA carboxylase (“ACC”) inhibitory activity and may be useful in treating ACC mediated diseases. Also provided herein are processes or steps for the preparation of a Compound I and intermediates useful for the processes or steps described herein.

公开(公告)号：US20210024537A1

公开(公告)日：2021-01-28

申请号：US16924924

申请日：2020-07-09

Applicant: Gilead Sciences, Inc.

Inventor： Michael Geier ,  Luke Humphreys ,  Norihiro Ikemoto ,  Sean Liew ,  Henry Morrison ,  Mark E. Scott ,  Vimal Varghese

IPC: C07D495/04 ,  C07D309/12 ,  C07D493/10 ,  A61P3/00 ,  C12P7/42

Abstract: The present disclosure provides solid forms, including a salt or co-crystal, of Compound I: which exhibits Acetyl-CoA carboxylase (“ACC”) inhibitory activity and may be useful in treating ACC mediated diseases. Also provided herein are processes or steps for the preparation of a Compound I and intermediates useful for the processes or steps described herein.

公开(公告)号：US20180298025A1

公开(公告)日：2018-10-18

申请号：US15910744

申请日：2018-03-02

Applicant: Gilead Sciences, Inc.

Inventor： Michael Geier ,  Luke Humphreys ,  Norihiro Ikemoto ,  Sean Liew ,  Henry Morrison ,  Mark E. Scott ,  Vimal Varghese

IPC: C07D495/04 ,  C07D309/12 ,  C12P7/42 ,  C07D493/10

Abstract: The present disclosure provides solid forms, including a salt or co-crystal, of Compound I: which exhibits Acetyl-CoA carboxylase (“ACC”) inhibitory activity and may be useful in treating ACC mediated diseases. Also provided herein are processes or steps for the preparation of a Compound I and intermediates useful for the processes or steps described herein.